The growth of blood vessels (a process known as angiogenesis) is essential for organ
growth and repair. An imbalance in this process contributes to numerous malignant …

Chronic obstructive pulmonary disease (COPD) is characterised by chronic inflammation of
the airways and progressive destruction of lung parenchyma, a process that in most cases is …

Chronic obstructive pulmonary diseases (COPD), comprised of pulmonary emphysema,
chronic bronchitis, and structural and inflammatory changes of small airways, is a leading …

The treatment of ocular neovascular diseases is being revolutionized by intravitreal
therapies targeting vascular endothelial growth factor (VEGF). Two agents are approved for …

Vascular endothelium plays a crucial role in vascular homeostasis and tissue fluid balance.
To target endothelium for robust genome editing, we developed poly (ethylene glycol) …

Vascular endothelial growth factor (VEGF) is a pluripotent growth and permeability factor
that has a broad impact on endothelial cell function. The lung tissue is very rich in this …

Acute respiratory distress syndrome is the most severe form of acute lung injury (ALI) and is
associated with significant mortality. Lipopolysaccharide (LPS)-induced injury is a valuable …

Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

Aims Endothelial‐derived epoxyeicosatrienoic acids may regulate vascular tone and are
metabolized by soluble epoxide hydrolase enzymes (sEH). GSK2256294 is a potent and …

Emphysema is one manifestation of a group of chronic, obstructive, and frequently
progressive destructive lung diseases. Cigarette smoking and air pollution are the main …