Hydrolases: catalytically promiscuous enzymes for non-conventional reactions in organic synthesis

E Busto, V Gotor-Fernández, V Gotor - Chemical Society Reviews, 2010 - pubs.rsc.org
During the last three decades the use of hydrolases for the catalysis of environmentally
friendly organic processes under mild reaction conditions has been well documented …

Applications of biotransformations and biocatalysis to complexity generation in organic synthesis

T Hudlicky, JW Reed - Chemical Society Reviews, 2009 - pubs.rsc.org
This tutorial review provides a survey of syntheses in which an enzymatic step contributed to
generating downstream molecular complexity in the target. The first part provides a guide to …

Novozym 435: the “perfect” lipase immobilized biocatalyst?

C Ortiz, ML Ferreira, O Barbosa… - Catalysis Science & …, 2019 - pubs.rsc.org
Novozym 435 (N435) is a commercially available immobilized lipase produced by
Novozymes. It is based on immobilization via interfacial activation of lipase B from Candida …

Epoxidation and Baeyer–Villiger oxidation using hydrogen peroxide and a lipase dissolved in ionic liquids

AJ Kotlewska, F van Rantwijk, RA Sheldon… - Green …, 2011 - pubs.rsc.org
Epoxidation and Baeyer–Villiger oxidation of olefins and (cyclic) ketones were successfully
carried out in hydrogen-bond-donating (HBD) ionic liquids, using a lipase-catalysed …

The Baeyer–Villiger oxidation of ketones: A paradigm for the role of soft Lewis acidity in homogeneous catalysis

RA Michelin, P Sgarbossa, A Scarso… - Coordination Chemistry …, 2010 - Elsevier
The Baeyer–Villiger oxidation of ketones to the corresponding esters or lactones is a
valuable transformation that has been upgraded several times over the last century, from the …

Highly active nanobiocatalyst from lipase noncovalently immobilized on multiwalled carbon nanotubes for Baeyer–Villiger synthesis of lactones

M Markiton, S Boncel, D Janas… - … Sustainable Chemistry & …, 2017 - ACS Publications
A new method for the chemo-enzymatic Baeyer–Villiger oxidation of cyclic ketones to
lactones in the presence of a new heterogeneous nanobiocatalyst consisting of Candida …

Enzymatic aerobic ring rearrangement of optically active furylcarbinols

D Thiel, D Doknić, J Deska - Nature Communications, 2014 - nature.com
Biogenic furans are currently discussed as highly attractive alternative feedstock in a post-
fossil society; thus, also the creation of sustainable furan valorization pathways appears of …

Chemo-enzymatic synthesis of key intermediates (S)-γ-hydroxymethyl-α, β-butenolide and (S)-γ-hydroxymethyl-γ-butyrolactone via lipase-mediated Baeyer–Villiger …

AL Flourat, AAM Peru, ARS Teixeira, F Brunissen… - Green …, 2015 - pubs.rsc.org
Levoglucosenone (LGO), a valuable chiral platform chemical that can be efficiently
produced from catalytic fast pyrolysis of cellulose, has been efficiently converted into …

A prospective life cycle assessment (LCA) of monomer synthesis: comparison of biocatalytic and oxidative chemistry

MAF Delgove, AB Laurent, JM Woodley… - …, 2019 - Wiley Online Library
Biotechnological processes are typically perceived to be greener than chemical processes.
A life cycle assessment (LCA) was performed to compare the chemical and biochemical …

Folate-decorated polymeric Pt (ii) prodrug micelles for targeted intracellular delivery and cytosolic glutathione-triggered release of platinum anticancer drugs

SJT Rezaei, V Amani, MR Nabid, N Safari… - Polymer …, 2015 - pubs.rsc.org
In this work, we have developed redox-responsive platinum (II) prodrug micelles based on
folate-poly (ethylene glycol)-b-poly (α-Pt (II)-SS-caprolactone/caprolactone)(FA-PEG-bP (α …