The rapid and enthusiastic adoption of single-cell RNA sequencing (scRNA-seq) has
demonstrated that this technology is far more than just another way to perform transcriptome …

Polyploids—organisms that have multiple sets of chromosomes—are common in certain
plant and animal taxa, and can be surprisingly stable. The evidence that has emerged from …

While transformation of the major monocot crops is currently possible, the process typically
remains confined to one or two genotypes per species, often with poor agronomics, and …

Maintenance of genome integrity is a key issue for all living organisms. Cells are constantly
exposed to DNA damage due to replication or transcription, cellular metabolic activities …

Size control of multicellular organisms poses a longstanding biological question that has
always fascinated scientists. Currently the question is far from being resolved because of the …

A great many cell types are necessary for the myriad capabilities of complex, multicellular
organisms. One interesting aspect of this diversity of cell type is that many cells in diploid …

Polyploidy is a frequent phenomenon in the eukaryotic world, but the biological properties of
polyploid cells are not well understood. During evolution, polyploidy is thought to be an …

In endoreplication cell cycles, known as endocycles, cells successively replicate their
genomes without segregating chromosomes during mitosis and thereby become polyploid …

Cell cycle regulation is of pivotal importance for plant growth and development. Although
plant cell division shares basic mechanisms with all eukaryotes, plants have evolved novel …

Legume plants host nitrogen-fixing endosymbiotic Rhizobium bacteria in root nodules. In
Medicago truncatula, the bacteria undergo an irreversible (terminal) differentiation mediated …