Cytokine regulation of endothelial cell function: from molecular level to the bedside

A Mantovani, F Bussolino, M Introna - Immunology today, 1997 - cell.com
Endothelial cells (ECs) participate in inflammatory and immune reactions by producing and
responding to cytokines. The molecular basis underlying the functional reprograming of …

The roles of TNFAIP 2 in cancers and infectious diseases

L Jia, Y Shi, Y Wen, W Li, J Feng… - Journal of cellular and …, 2018 - Wiley Online Library
TNF α‐induced protein 2 (TNFAIP 2) is a primary response gene of TNF α. TNFAIP 2 is
highly expressed in immune cells and the urinary bladder. The expression of TNFAIP 2 is …

Extensive and divergent circadian gene expression in liver and heart

KF Storch, O Lipan, I Leykin, N Viswanathan, FC Davis… - Nature, 2002 - nature.com
Many mammalian peripheral tissues have circadian clocks,,,; endogenous oscillators that
generate transcriptional rhythms thought to be important for the daily timing of physiological …

M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex

K Hase, S Kimura, H Takatsu, M Ohmae, S Kawano… - Nature cell …, 2009 - nature.com
Cell–cell communication is essential for the development and homeostasis of multicellular
organisms. Recently, a new type of cell–cell communication was discovered that is based on …

Protective effect of the tunneling nanotube-TNFAIP2/M-sec system on podocyte autophagy in diabetic nephropathy

F Barutta, S Bellini, S Kimura, K Hase, B Corbetta… - Autophagy, 2023 - Taylor & Francis
Podocyte injury leading to albuminuria is a characteristic feature of diabetic nephropathy
(DN). Hyperglycemia and advanced glycation end products (AGEs) are major determinants …

Endogenous retrovirus-derived enhancers confer the transcriptional regulation of human trophoblast syncytialization

M Yu, X Hu, Z Pan, C Du, J Jiang, W Zheng… - Nucleic Acids …, 2023 - academic.oup.com
Endogenous retroviruses (ERVs) have been proposed as a driving force for the evolution of
the mammalian placenta, however, the contribution of ERVs to placental development and …

Calcium and 1α, 25‐dihydroxyvitamin D3 target the TNF‐α pathway to suppress experimental inflammatory bowel disease

Y Zhu, BD Mahon, M Froicu… - European journal of …, 2005 - Wiley Online Library
Vitamin D‐deficient IL‐10 knockout (KO) mice develop accelerated inflammatory bowel
disease (IBD). Removing dietary calcium from the diets of vitamin D‐deficient IL‐10 KO mice …

KLF5 promotes breast cancer proliferation, migration and invasion in part by upregulating the transcription of TNFAIP2

L Jia, Z Zhou, H Liang, J Wu, P Shi, F Li, Z Wang… - Oncogene, 2016 - nature.com
The Kruppel-like factor 5 (KLF5) transcription factor is highly expressed in high-grade and
basal-like breast cancers. However, the mechanism by which KLF5 promotes cell migration …

[HTML][HTML] A unique macrophage subpopulation signals directly to progenitor cells to promote regenerative neurogenesis in the zebrafish spinal cord

L Cavone, T McCann, LK Drake, EA Aguzzi… - Developmental cell, 2021 - cell.com
Central nervous system injury re-initiates neurogenesis in anamniotes (amphibians and
fishes), but not in mammals. Activation of the innate immune system promotes regenerative …

Subunit structure of the mammalian exocyst complex

Y Kee, JS Yoo, CD Hazuka… - Proceedings of the …, 1997 - National Acad Sciences
The exocyst is a protein complex required for the late stages of secretion in yeast. Unlike the
SNAREs (SNAP receptors), important secretory proteins that are broadly distributed on the …