[HTML][HTML] Polyethylenimine (PEI) in gene therapy: Current status and clinical applications

J Casper, SH Schenk, E Parhizkar, P Detampel… - Journal of Controlled …, 2023 - Elsevier
Polyethlyenimine (PEI) was introduced 1995 as a cationic polymer for nucleic acid delivery.
PEI and its derivatives are extensively used in basic research and as reference formulations …

Advances in 3D printing for tissue engineering

A Zaszczyńska, M Moczulska-Heljak, A Gradys… - Materials, 2021 - mdpi.com
Tissue engineering (TE) scaffolds have enormous significance for the possibility of
regeneration of complex tissue structures or even whole organs. Three-dimensional (3D) …

Chemically tailored molecular surface modification of cellulose nanofibrils for manipulating the charge density of triboelectric nanogenerators

Y Liu, Q Fu, J Mo, Y Lu, C Cai, B Luo, S Nie - Nano Energy, 2021 - Elsevier
Studying the surface chemical composition of materials is greatly significant to further
understand the triboelectric charge generated during contact electrification. Although it has …

Microvesicles transfer mitochondria and increase mitochondrial function in brain endothelial cells

A D'Souza, A Burch, KM Dave, A Sreeram… - Journal of Controlled …, 2021 - Elsevier
We have demonstrated, for the first time that microvesicles, a sub-type of extracellular
vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer …

Formation of Triboelectric Series via Atomic-Level Surface Functionalization for Triboelectric Energy Harvesting

SH Shin, YE Bae, HK Moon, J Kim, SH Choi, Y Kim… - ACS …, 2017 - ACS Publications
Triboelectric charging involves frictional contact of two different materials, and their contact
electrification usually relies on polarity difference in the triboelectric series. This limits the …

Polyplex evolution: understanding biology, optimizing performance

A Hall, U Lächelt, J Bartek, E Wagner, SM Moghimi - Molecular Therapy, 2017 - cell.com
Polyethylenimine (PEI) is a gold standard polycationic transfectant. However, the highly
efficient transfecting activity of PEI and many of its derivatives is accompanied by serious …

The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent

V Vaijayanthimala, PY Cheng, SH Yeh, KK Liu… - Biomaterials, 2012 - Elsevier
Nanocarbon is a promising type of biomaterial for diagnostic and therapeutic applications.
Fluorescent nanodiamond (FND) containing nitrogen-vacancy centers as built-in …

Recent advances in nanotechnology approaches for non-viral gene therapy

Y Jiang, M Fan, Z Yang, X Liu, Z Xu, S Liu… - Biomaterials …, 2022 - pubs.rsc.org
Gene therapy has shown great potential in the treatment of many diseases by
downregulating the expression of certain genes. The development of gene vectors as a …

Nanoparticle delivery systems in cancer vaccines

Y Krishnamachari, SM Geary, CD Lemke… - Pharmaceutical …, 2011 - Springer
Therapeutic strategies that involve the manipulation of the host's immune system are gaining
momentum in cancer research. Antigen-loaded nanocarriers are capable of being actively …

Non-viral gene delivery systems for tissue repair and regeneration

P Wu, H Chen, R Jin, T Weng, JK Ho, C You… - Journal of translational …, 2018 - Springer
Critical tissue defects frequently result from trauma, burns, chronic wounds and/or surgery.
The ideal treatment for such tissue loss is autografting, but donor sites are often limited …