Myeloid sarcoma, chloroma, or extramedullary acute myeloid leukemia tumor: a tale of misnomers, controversy and the unresolved

RM Shallis, RP Gale, HM Lazarus, KB Roberts, ML Xu… - Blood reviews, 2021 - Elsevier
Abstract The World Health Organization classification and definition of “myeloid sarcoma” is
imprecise and misleading. A more accurate term is “extramedullary acute myeloid leukemia …

Blastic plasmacytoid dendritic cell neoplasm: a comprehensive review in pediatrics, adolescents, and young adults (AYA) and an update of novel therapies

B Cuglievan, J Connors, J He, S Khazal, S Yedururi… - Leukemia, 2023 - nature.com
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that
can involve the bone marrow, peripheral blood, skin, lymph nodes, and the central nervous …

Ultraviolet radiation shapes dendritic cell leukaemia transformation in the skin

GK Griffin, CAG Booth, K Togami, SS Chung, D Ssozi… - Nature, 2023 - nature.com
Tumours most often arise from progression of precursor clones within a single anatomical
niche. In the bone marrow, clonal progenitors can undergo malignant transformation to …

Sex-Biased ZRSR2 Mutations in Myeloid Malignancies Impair Plasmacytoid Dendritic Cell Activation and Apoptosis

K Togami, SS Chung, V Madan, CAG Booth… - Cancer discovery, 2022 - AACR
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive leukemia of
plasmacytoid dendritic cells (pDC). BPDCN occurs at least three times more frequently in …

North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need

N Pemmaraju, H Kantarjian, K Sweet, E Wang… - Blood, 2023 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy
with historically poor outcomes and no worldwide consensus treatment approach. Unique …

Plasmacytoid dendritic cells proliferation associated with acute myeloid leukemia: phenotype profile and mutation landscape

L Zalmaï, PJ Viailly, S Biichle, M Cheok… - …, 2020 - pmc.ncbi.nlm.nih.gov
Neoplasms involving plasmacytoid dendritic cells (pDC) include blastic pDC neoplasms
(BPDCN) and other pDC proliferations, where pDC are associated with myeloid …

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1-mutated acute myeloid leukemia

W Xiao, A Chan, MR Waarts, T Mishra… - Blood, The Journal …, 2021 - ashpublications.org
Plasmacytoid dendritic cells (pDCs) are the principal natural type I interferon–producing
dendritic cells. Neoplastic expansion of pDCs and pDC precursors leads to blastic …

Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis

HS Murthy, MJ Zhang, K Chen, S Ahmed… - Blood …, 2023 - ashpublications.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematological malignancy
with a poor prognosis and considered incurable with conventional chemotherapy. Small …

Transcriptomic and genomic heterogeneity in blastic plasmacytoid dendritic cell neoplasms: from ontogeny to oncogenesis

F Renosi, A Roggy, A Giguelay, L Soret… - Blood …, 2021 - ashpublications.org
Oncogenesis and ontogeny of blastic plasmacytoid dendritic cell neoplasm (BPDCN) remain
uncertain, between canonical plasmacytoid dendritic cells (pDCs) and AXL+ SIGLEC6+ DCs …

Immunophenotypic characterization of reactive and neoplastic plasmacytoid dendritic cells permits establishment of a ten-color flow cytometric panel for initial workup …

W Wang, JD Khoury, RN Miranda… - …, 2020 - pmc.ncbi.nlm.nih.gov
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematopoietic neoplasm
whose immunophenotype remains incompletely characterized, particularly with regards to …