Introduction Obesity is a chronic disease responsible for a high morbidity and mortality rate,
with an increasing worldwide prevalence. Obesity is associated with immune responses …

The prevalence of type 2 diabetes mellitus (T2DM) and its major risk factor, obesity, has
reached epidemic proportions in Western society. How obesity leads to insulin resistance …

Men have a higher tendency to accumulate abdominal visceral fat compared to pre-
menopausal women. The accumulation of abdominal visceral fat in men, which is a strong …

Late-onset hypogonadism (ie androgen deficiency) raises the risk for abdominal obesity in
men. The mechanism for this obesity is unclear. Here, we demonstrated that hypogonadism …

Insulin resistance, a hallmark of metabolic disorders, is a risk factor for diabetes and
cardiovascular disease. Impairment of insulin responsiveness in vascular endothelium …

Insulin resistance has been shown to be associated with cardiac sympathovagal imbalance,
myocardial dysfunction, and cardiac mitochondrial dysfunction. Whereas metformin is a …

The ameliorating effects of ginsenoside Re (G Re) on high fat diet (HFD)-induced insulin
resistance in C57BL/6 mice were investigated to assess its physiological function. In the …

Background: Obesity leads to a chronic inflammatory state, endothelial dysfunction and
hypertension. Objective: To establish the time-course of events regarding inflammatory …

Abstract Background Metabolic syndrome (MetS) is associated with an increased risk of
cerebrovascular diseases, including cerebral ischemia. Microvascular dysfunction is an …

Vascular endothelial dysfunction is caused by dyslipidemia, hypertension, and deficiency of
antioxidant systems. In this study, the protective effect of a flavonol, morin was investigated …