The microcirculation is responsible for orchestrating adjustments in vascular tone to match
local tissue perfusion with oxygen demand. Beyond this metabolic dilation, the …

Abstract Small arterioles (40–150 μm) contribute to the majority of vascular resistance within
organs and tissues. Under resting conditions, the basal tone of these vessels is determined …

Exercise is a primary stimulus for increased myocardial oxygen demand. The~ 6-fold
increase in oxygen demand of the left ventricle during heavy exercise is met principally by …

Atherosclerosis of conduit epicardial arteries is the principal culprit behind the complications
of coronary heart disease, but a growing body of literature indicates that the coronary …

The heart is one of the most demanding organs of the human body. The high nutrient and
oxygen demands need to be met through an adequate vascularization of the myocardium. In …

Myocardial infarction (MI) is associated with endothelial dysfunction resulting in an
imbalance in endothelium-derived vasodilators and vasoconstrictors. We have previously …

Microcirculation is the terminal vascular network where the exchange of substances
between the blood and the tissues occurs. Usually, the term refers to functional unit …

Cystic fibrosis is a lethal autosomal recessive disease, caused by a defect of the cystic
fibrosis transmembrane conductance regulator (CFTR), which is characterised by lung …

The coronary microcirculation is the principle site of blood flow control and myocardium
oxygen delivery within the coronary artery tree. Coronary arteriole tone is determined by …

RESUMO JUNQUEIRA, Camillo de Léllis Carneiro. Microcirculação e biomarcadores em
indivíduos com hipertensão arterial resistente, hipertensão leve a moderada e em …