Immunopotentiating significance of conventionally used plant adaptogens as modulators in biochemical and molecular signalling pathways in cell mediated …

P Kaur, VO Makanjuola, R Arora, B Singh… - Biomedicine & …, 2017 - Elsevier
Natural products are of great surge in the identification of chemopreventive agents and
biologically active molecules for the development of new promising therapeutic agents …

The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases—Part III: In-silico molecular docking investigations

IV Ogungbe, WN Setzer - Molecules, 2016 - mdpi.com
Malaria, leishmaniasis, Chagas disease, and human African trypanosomiasis continue to
cause considerable suffering and death in developing countries. Current treatment options …

Quassia amara bioactive compounds as a Novel DPP-IV inhibitor: an in-silico study

EA Olugbogi, DS Bodun, SD Omoseeye… - Bulletin of the National …, 2022 - Springer
Background Diabetes, a cardiometabolic condition with social and health ramifications, is
already a global epidemic. Diabetes affects 422 million people worldwide, with the majority …

Computational evaluation of bioactive compounds from Vitis vinifera as a novel β-catenin inhibitor for cancer treatment

AO Adebesin, AO Ayodele, O Omotoso… - Bulletin of the National …, 2022 - Springer
Background β-catenin is an important unit of the Wnt/β-catenin signaling pathway, a
conserved process involving several physiological activities, encompassing differentiation …

[PDF][PDF] In silico investigation of black tea components on α-amylase, α-glucosidase and lipase

S Mohapatra, A Prasad, F Haque, S Ray… - Journal of Applied …, 2015 - japsonline.com
Black tea is one of the most widely consumed beverages in the world and traditionally
known for its antidiabetic and antiobesity property. However, the underlying mechanisms of …

Identification of apposite antagonist for androgen receptor in prostate cancer: an in silico study of fenugreek compounds

EA Olugbogi, OA Arobadade, DS Bodun… - Journal of …, 2023 - Taylor & Francis
Abstract Benign Prostate Cancer (BPC), a prevalent condition predominantly affecting
elderly males, manifests with voiding difficulties and urinary retention. A library of …

Targeting Peroxisome Proliferator-Activated Receptor-β/δ, Reactive Oxygen Species and Redox Signaling with Phytocompounds for Cancer Therapy

C Kaur, SK Sahu, K Bansal, LK DeLiberto… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Peroxisome proliferator-activated receptors (PPARs) have a moderately
preserved amino-terminal domain, an extremely preserved DNA-binding domain, an integral …

[HTML][HTML] Molecular modeling and docking study to elucidate novel chikungunya virus nsP2 protease inhibitors

T Agarwal, S Asthana, A Bissoyi - Indian Journal of Pharmaceutical …, 2015 - ncbi.nlm.nih.gov
Chikungunya is one of the tropical viral infections that severely affect the Asian and African
countries. Absence of any suitable drugs or vaccines against Chikungunya virus till date …

Bioactive compounds found in Cucumis sativus demonstrate optimal binding affinity to PTP1B.

OE Ogunbiyi, BT Ogunbiyi… - IPS Journal of …, 2023 - drugdiscoveryupdate.com
Diabetes mellitus is a group of cardiometabolic disorders defined by elevated blood sugar
levels. The majority of people affected by this disease reside in rural areas of low-and …

[PDF][PDF] Computational prediction of HCV RNA polymerase inhibitors from alkaloid library

SO Olubode, OI Omotuyi… - Letters in Applied Nano …, 2021 - researchgate.net
Hepatitis C virus (HCV) is a global challenge and the leading cause of chronic liver disease.
Approximately 30% of a patient infected with chronic HCV results into liver cirrhosis. WHO …