It is now well established that small RNAs (sRNAs) have diverse and widespread roles in
regulating gene expression in all organisms (1–4). Mechanisms of action are varied but can …

Cystic fibrosis (CF) is the most life-limiting autosomal recessive disorder in Caucasians. CF
is characterized by abnormal viscous secretions that impair the function of several tissues …

Genome analysis of strains placed in the NCBI genome database as Burkholderia
cenocepacia defined nine genomic species groups. The largest group (259 strains) …

Background Burkholderia cenocepacia is a human opportunistic pathogen causing
devastating symptoms in patients suffering from immunodeficiency and cystic fibrosis. Out of …

In C. crescentus, iron metabolism is mainly controlled by the transcription factor Fur (ferric
uptake regulator). Iron-bound Fur represses genes related to iron uptake and can directly …

Small non-coding RNAs (sRNAs) are key regulators of post-transcriptional gene expression
in bacteria. Hundreds of sRNAs have been found using in silico genome analysis and …

The investigation of common and specific mechanisms of pathogenesis and persistence of
these bacteria in the host may contribute to future investigations and identifications of …

Background Salmonella enterica possess several iron acquisition systems, encoded on the
chromosome and plasmids. Recently, we demonstrated that incompatibility group (Inc) FIB …

Recombination and positive selection are two key factors that play a vital role in pathogenic
microorganisms' population adaptation and diversification. The Burkholderia cepacia …

Burkholderia cenocepacia J2315 is a member of the B. cepacia complex. It has a large
genome with three replicons and one plasmid; 7,261 genes code for annotated proteins …