A microfluidic system for causing perturbations in a cell membrane, the system including a
microfluidic channel defining a lumen and being configured such that a cell suspended in a …

A method and device for preferentially delivering a compound such as an antigen to the
cytosol of an immune cell. The method comprises passing a cell suspension comprising the …

The current subject matter includes methods, systems, articles, and techniques to deliver
material to anucleate cells, such as red blood cells. Using a rapid deformation based …

Isolating or identifying a cell based on a physical property of said cell can include providing
a cell suspension; passing said suspension through a microfluidic channel that includes a …

Gene editing can be performed by introducing gene-editing components into a cell by
mechanical cell disruption. Related apparatus, systems, techniques, and articles are also …

Isolating or identifying a cell based on a physical property of said cell can include providing
a cell suspension; passing said suspension through a microfluidic channel that includes a …

US10724043B2 - Multi-pulse transfection methods and cells - Google Patents US10724043B2
- Multi-pulse transfection methods and cells - Google Patents Multi-pulse transfection methods …

The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells wherein the CAR T cells …

The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells and a small molecule …

Described herein are methods and systems for mechanoporation-based high-throughput
payload delivery into biological cells. For example, one system can process at least 1 billion …