In evaluating the pathogenesis of periodontal diseases, the diagnostic potential of gingival
crevicular fluid has been extensively explored during the last twenty years, from initially just …

Objectives The holy grail of biomarker research in periodontology is to develop a high
impact diagnostics which have a significant impact on clinical decision-making, patient …

Bone marrow mesenchymal stem cell-derived small extracellular vesicles (BMSC-sEVs) can
be used as a potential cell-free strategy for periodontal tissue regeneration, and we aim to …

Background Periodontitis is a polymicrobial biofilm-induced inflammatory disease that
affects 743 million people worldwide. The current model to explain periodontitis progression …

MicroRNAs (miRNAs) have been shown to be major regulators of eukaryotic gene
expression. However, bacterial RNAs comparable in size to eukaryotic miRNAs (18–22 …

Coronary artery disease is an inflammatory disorder characterized by narrowing of coronary
arteries due to atherosclerotic plaque formation. To date, the accumulated epidemiological …

Background: Current publications present contradictory findings regarding interleukin-8 (IL-
8) levels in patients with chronic periodontitis (CP). This systematic review compile …

Background: Periodontitis is an immune-inflammatory disease that leads to the progressive
destruction of bone and connective tissue in the periodontal area. The cytokine network …

The last few decades have witnessed an increasing interest in studying the human
microbiome and its role in health and disease. The focus of those studies was mainly the …

Atherosclerosis (AS), one of the most common types of cardiovascular disease, has initially
been attributed to the accumulation of fats and fibrous materials. However, more and more …