Glucocorticoids are a class of anti-inflammatory drugs commonly used to treat various ocular
and systemic conditions. Although the role of glucocorticoids in the treatment of numerous …

Glaucoma remains only partially understood, particularly at the level of intraocular pressure
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …

With the combined purpose of facilitating useful vision over a lifetime, a number of ocular
cells have evolved specialized features not found elsewhere in the body. The trabecular …

The extracellular matrix (ECM) of the trabecular meshwork (TM) is thought to be important in
regulating intraocular pressure (IOP) in both normal and glaucomatous eyes. IOP is …

Glaucoma is a blinding optic neuropathy, the main risk factor for which is increased
intraocular pressure (IOP). The trabecular meshwork, located within the iridocorneal angle …

Current understanding of conventional outflow dysfunction in... : Current Opinion in
Ophthalmology Current understanding of conventional outflow dysfunction in glaucoma …

Transforming growth factor-β2 (TGF-β2) is found in increasing amounts in aqueous humor
and reactive optic nerve astrocytes of patients with primary open-angle glaucoma (POAG), a …

Glaucoma is a progressive and chronic neurodegenerative disorder characterized by
damage to the inner layers of the retina and deformation of the optic nerve head. The …

Purpose: Treatment with corticosteroids can result in ocular hypertension and may lead to
the development of steroid-induced glaucoma. The extent to which biomechanical changes …

Elevation of intraocular pressure (IOP) due to therapeutic use of glucocorticoids is called
steroid-induced ocular hypertension (SIOH); this can lead to steroid-induced glaucoma …