Sickle cell disease is the most common cause of stroke in childhood, both ischaemic and
haemorrhagic, and it also affects adults with the condition. Without any screening or …

Both ischemic and hemorrhagic strokes in children can be a complication of sickle cell
disease, which also affects adults. The occurrence is high without any screening or …

Background Sickle cell disease is the most common severe monogenic disorder in humans.
In Africa, 50–90% of children born with sickle cell disease die before they reach their fifth …

Background Most of the world's sickle cell disease (SCD) burden is in Africa, where it is a
major contributor to child morbidity and mortality. Despite the low cost of many preventive …

Abstract Background The World Health Organization recommends not performing
transfusions in African children hospitalized for uncomplicated severe anemia (hemoglobin …

Background Malnutrition continues to affect under-five children in Africa to an overwhelming
proportion. The situation is further compounded by the burden of sickle cell disease (SCD) …

Sickle cell anemia (SCA) is the commonest life-threatening genetic disorder in tropical
regions, particularly in sub-Saharan Africa. It has been estimated that between 50–90% of …

Background: Anemia is a wide-spread public health problem characterized by a decrease in
hemoglobin concentration and/or red blood cell volume below an established cut-off value …

Abstract Background and Objective The disease burden of sickle cell anemia (SCA) in sub-
Saharan African (SSA) countries is substantial, with many children dying without an …

Sickle cell disease (SCD) can significantly impair the health-related quality of life (HRQOL)
of children and adolescents. This review aimed to assess current evidence regarding the …