Invited Review Article: Review of centrifugal microfluidic and bio-optical disks

DD Nolte - Review of scientific instruments, 2009 - pubs.aip.org
Spinning biodisks have advantages that make them attractive for specialized biochip
applications. The two main classes of spinning biodisks are microfluidic disks and bio …

Bio-optical compact dist system

DD Nolte, FE Regnier, M Varma - US Patent 6,685,885, 2004 - Google Patents
(57) ABSTRACT A device for identifying analytes in a biological Sample, including a
Substrate having a Surface lying Substantially in a first plane, a plurality of targets, each …

[图书][B] Optical interferometry for biology and medicine

DD Nolte - 2011 - books.google.com
This book presents the fundamental physics of optical interferometry as applied to
biophysical, biological and medical research. Interference is at the core of many types of …

Time-dependent speckle in holographic optical coherence imaging and the health of tumor tissue

P Yu, L Peng, M Mustata, JJ Turek, MR Melloch… - Optics Letters, 2004 - opg.optica.org
Holographic optical coherence imaging acquires en face images from successive depths
inside scattering tissue. In a study of multicellular tumor spheroids the holographic features …

Holographic optical coherence imaging of tumor spheroids

P Yu, M Mustata, JJ Turek, PMW French… - Applied physics …, 2003 - pubs.aip.org
We present depth-resolved coherence-domain images of living tissue using a dynamic
holographic semiconductor film. An AlGaAs photorefractive quantum-well device is used in …

Holographic optical coherence imaging of rat osteogenic sarcoma tumor spheroids

P Yu, M Mustata, L Peng, JJ Turek, MR Melloch… - Applied …, 2004 - opg.optica.org
Holographic optical coherence imaging is a full-frame variant of coherence-domain imaging.
An optoelectronic semiconductor holographic film functions as a coherence filter placed …

Adaptive interferometry of protein on a BioCD

L Peng, MM Varma, W Cho, FE Regnier, DD Nolte - Applied optics, 2007 - opg.optica.org
Adaptive spinning-disk interferometry is capable of measuring surface profiles of a thin
biolayer with subnanometer longitudinal resolution. High-speed phase modulation in the …

Differential phase-contrast BioCD biosensor

M Zhao, W Cho, F Regnier, D Nolte - Applied Optics, 2007 - opg.optica.org
Common-path differential phase-contrast interferometry measures the spatial gradient of
surface dipole density on a bio-optical compact disk (BioCD) and is sensitive to small …

Spinning-disk interferometry: The biocd

DD Nolte, FE Regnier - Optics and photonics news, 2004 - opg.optica.org
October 2004■ Optics & Photonics News 49 wave-front-splitting null interferometer, which
can be understood by considering Fig. 1. By carefully selecting the focusing lens, a …

System with extended range of molecular sensing through integrated multi-modal data acquisition

X Wang, DD Nolte, M Varma, B Weichel… - US Patent …, 2010 - Google Patents
A multi-modal data acquisition system for detecting target material on a biological reaction
surface, the system comprising a radiation source for generating an incoming beam that …