[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment

M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …

Nanomedical approaches in the realm of rheumatoid arthritis

AF Radu, SG Bungau - Ageing research reviews, 2023 - Elsevier
Rheumatoid arthritis (RA) is a heterogeneous autoimmune inflammatory disorder defined by
the damage to the bone and cartilage in the synovium, which causes joint impairment and …

pH‐responsive polymer nanoparticles for drug delivery

N Deirram, C Zhang, SS Kermaniyan… - Macromolecular …, 2019 - Wiley Online Library
Stimuli‐responsive nanoparticles have the potential to improve the delivery of therapeutics
to a specific cell or region within the body. There are many stimuli that have shown potential …

Towards an arthritis flare-responsive drug delivery system

N Joshi, J Yan, S Levy, S Bhagchandani… - Nature …, 2018 - nature.com
Local delivery of therapeutics for the treatment of inflammatory arthritis (IA) is limited by short
intra-articular half-lives. Since IA severity often fluctuates over time, a local drug delivery …

[HTML][HTML] Nanomedicines for the treatment of rheumatoid arthritis: State of art and potential therapeutic strategies

Q Wang, X Qin, J Fang, X Sun - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Increasing understanding of the pathogenesis of rheumatoid arthritis (RA) has remarkably
promoted the development of effective therapeutic regimens of RA. Nevertheless, the …

3D printing of poly (propylene fumarate) oligomers: Evaluation of resin viscosity, printing characteristics and mechanical properties

Y Luo, G Le Fer, D Dean, ML Becker - Biomacromolecules, 2019 - ACS Publications
Complex three-dimensional (3D) pore geometries, useful for tissue engineering scaffolds,
can be fabricated via photo-crosslinking of resorbable poly (propylene fumarate)(PPF) …

Knee osteoarthritis therapy: recent advances in intra-articular drug delivery systems

L Ma, X Zheng, R Lin, ARJ Sun, J Song… - Drug design …, 2023 - Taylor & Francis
Drug delivery for osteoarthritis (OA) treatment is a continuous challenge because of their
poor bioavailability and rapid clearance in joints. Intra-articular (IA) drug delivery is a …

4D printing of resorbable complex shape-memory poly (propylene fumarate) star scaffolds

G Le Fer, ML Becker - ACS applied materials & interfaces, 2020 - ACS Publications
3D/4D printing is enabling transformative advances in device manufacturing and medicine
but remains limited by the lack of printable resorbable materials with advanced properties …

Acid-sensitive prodrugs; a promising approach for site-specific and targeted drug release

A Nazli, MZI Khan, Á Rácz, S Béni - European Journal of Medicinal …, 2024 - Elsevier
Drugs administered through conventional formulations are devoid of targeting and often
spread to various undesired sites, leading to sub-lethal concentrations at the site of action …

Localized and targeted delivery of NSAIDs for treatment of inflammation: A review

RM Haley, HA von Recum - Experimental Biology and …, 2019 - journals.sagepub.com
Inflammatory processes are increasingly being identified at the core of many different
disease states (eg heart disease, cancer, diabetes). As such, anti-inflammatory strategies …