Rheumatoid arthritis (RA) is a heterogeneous autoimmune inflammatory disorder defined by the damage to the bone and cartilage in the synovium, which causes joint impairment and …
N Deirram, C Zhang, SS Kermaniyan… - Macromolecular …, 2019 - Wiley Online Library
Stimuli‐responsive nanoparticles have the potential to improve the delivery of therapeutics to a specific cell or region within the body. There are many stimuli that have shown potential …
Local delivery of therapeutics for the treatment of inflammatory arthritis (IA) is limited by short intra-articular half-lives. Since IA severity often fluctuates over time, a local drug delivery …
Q Wang, X Qin, J Fang, X Sun - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Increasing understanding of the pathogenesis of rheumatoid arthritis (RA) has remarkably promoted the development of effective therapeutic regimens of RA. Nevertheless, the …
Complex three-dimensional (3D) pore geometries, useful for tissue engineering scaffolds, can be fabricated via photo-crosslinking of resorbable poly (propylene fumarate)(PPF) …
L Ma, X Zheng, R Lin, ARJ Sun, J Song… - Drug design …, 2023 - Taylor & Francis
Drug delivery for osteoarthritis (OA) treatment is a continuous challenge because of their poor bioavailability and rapid clearance in joints. Intra-articular (IA) drug delivery is a …
G Le Fer, ML Becker - ACS applied materials & interfaces, 2020 - ACS Publications
3D/4D printing is enabling transformative advances in device manufacturing and medicine but remains limited by the lack of printable resorbable materials with advanced properties …
A Nazli, MZI Khan, Á Rácz, S Béni - European Journal of Medicinal …, 2024 - Elsevier
Drugs administered through conventional formulations are devoid of targeting and often spread to various undesired sites, leading to sub-lethal concentrations at the site of action …
RM Haley, HA von Recum - Experimental Biology and …, 2019 - journals.sagepub.com
Inflammatory processes are increasingly being identified at the core of many different disease states (eg heart disease, cancer, diabetes). As such, anti-inflammatory strategies …