Salmonella injects over 40 virulence factors, termed effectors, into host cells to subvert
diverse host cellular processes. Of these 40 Salmonella effectors, at least 25 have been …

Monitoring of pathogenic bacteria plays a vital role in precluding foodborne disease
outbreaks. In this research work, a genosensor based on innovative label-free DNA was …

Bacterial effector proteins, delivered into host cells by specialized multiprotein secretion
systems, are a key mediator of bacterial pathogenesis. Following delivery, they modulate a …

The subcellular localization and intracellular trafficking of Toll‐like receptors (TLRs) critically
regulate TLRs‐mediated antimicrobial immunity and autoimmunity. Here, it is demonstrated …

Aloe-emodin (1, 8-dihydroxy-3-hydroxymethyl-anthraquinone), derived from some Chinese
edible medicinal herbs, exerts a potential anticancer activity on various cancer cells, making …

Increasing evidence highlights the role of bacteria in promoting tumorigenesis. The
underlying mechanisms may be diverse and remain poorly understood. Here, we report that …

Autophagy is a fundamental cellular process that has important roles in innate and adaptive
immunity against a broad range of microbes. Many pathogenic microbes have evolved …

Death receptor signaling is critical for cell death, inflammation, and immune homeostasis.
Hijacking death receptors and their corresponding adaptors through type III secretion system …

During infection, Salmonella species inject multiple type III secretion system (T3SS) effector
proteins into host cells that mediate invasion and subsequent intracellular replication. At …

Modulation of cell death is a powerful strategy employed by pathogenic bacteria to evade
host immune clearance and occupy profitable replication niches during infection …