Discovery of Frenolicin B as Potential Agrochemical Fungicide for Controlling Fusarium Head Blight on Wheat

C Han, Z Yu, Y Zhang, Z Wang, J Zhao… - Journal of Agricultural …, 2021 - ACS Publications
In this study, the supernatant extract from fermentation broth of Streptomyces sp. NEAU-H3
showed strong antifungal activity against Fusarium graminearum strain PH-1 in vitro and in …

Frenolicins C–G, Pyranonaphthoquinones from Streptomyces sp. RM-4-15

X Wang, KA Shaaban, SI Elshahawi… - Journal of natural …, 2013 - ACS Publications
Appalachian active coal fire sites were selected for the isolation of bacterial strains
belonging to the class actinobacteria. A comparison of high-resolution electrospray …

Frenolicin B targets peroxiredoxin 1 and glutaredoxin 3 to trigger ROS/4E-BP1-mediated antitumor effects

Q Ye, Y Zhang, Y Cao, X Wang, Y Guo, J Chen… - Cell chemical …, 2019 - cell.com
Summary Peroxiredoxin 1 (Prx1) and glutaredoxin 3 (Grx3) are two major antioxidant
proteins that play a critical role in maintaining redox homeostasis for tumor progression …

Dimeric pyranonaphthoquinones: Isolation, bioactivity, and synthetic approaches

RA Fernandes, PH Patil… - European Journal of …, 2016 - Wiley Online Library
The dimeric pyranonaphthoquinones,“bis versions” of the naphtho [2, 3‐c] pyran‐5, 10‐
dione moiety, comprises a group of antibiotics that have been isolated from a variety of …

Multicomponent synthesis of novel 3-benzoyl-4h-benzo [g] chromene-5, 10-dione derivatives

G Le-Nhat-Thuy, TAD Thi, PH Thi, QGN Thi… - Tetrahedron …, 2021 - Elsevier
An efficient method was developed to prepare a series of novel 3-benzoyl-4H-benzo [g]
chromene-5, 10-dione derivatives from 2-hydroxy-1, 4-naphthoquinone, aromatic aldehydes …

Total synthesis of griseusins and elucidation of the griseusin mechanism of action

Y Zhang, Q Ye, LV Ponomareva, Y Cao, Y Liu… - Chemical …, 2019 - pubs.rsc.org
A divergent modular strategy for the enantioselective total synthesis of 12 naturally-occurring
griseusin type pyranonaphthoquinones and 8 structurally-similar analogues is described …

Enantioselective synthesis of 4 H-pyranonaphthoquinones via sequential squaramide and silver catalysis

U Kaya, P Chauhan, D Hack, K Deckers… - Chemical …, 2016 - pubs.rsc.org
An enantioselective one-pot Michael addition/hydroalkoxylation reaction between 2-hydroxy-
1, 4-naphthoquinones and alkyne-tethered nitroalkenes catalyzed by a cinchona-derived …

A Diastereoselective Oxa-Pictet–Spengler-Based Strategy for (+)-Frenolicin B and epi-(+)-Frenolicin B Synthesis

Y Zhang, X Wang, M Sunkara, Q Ye… - Organic …, 2013 - ACS Publications
An efficient diastereoselective oxa-Pictet–Spengler reaction strategy was developed to
construct benzoisochroman diastereomers. The utility of the reaction was demonstrated in …

Solvent-free synthesis of 4H-pyranonaphthoquinones using highly active and stable polymer-grafted layered double hydroxides (LDHs-g-POEGMA) as an efficient …

SK Krishnammagari, SM Lee, YT Jeong - Research on Chemical …, 2018 - Springer
Abstract Benzo [g] chromene-5, 10-diones (chromene-diones) have been synthesized by an
efficient, simple and green one-pot domino protocol by multi-component condensation of 2 …

Pyranonaphthoquinone compounds and methods of use thereof

JS Thorson, QB She, BD Anderson, Q Ye… - US Patent App. 15 …, 2018 - Google Patents
2017-12-20 Assigned to UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
reassignment UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION ASSIGNMENT OF …