Reactive oxygen species (ROS) are recently proposed to be involved in tumor metastasis
which is a complicated processes including epithelial–mesenchymal transition (EMT) …

Both structural and inflammatory cells are capable of secreting transforming growth factor
(TGF)‐β and expressing TGF‐β receptors. TGF‐β can induce multiple cellular responses …

Prognosis of basal breast cancers is poor but heterogeneous. Medullary breast cancers
(MBC) display a basal profile, but a favorable prognosis. We hypothesized that a previously …

Medullary breast cancer (MBC) is a rare but enigmatic pathologic type of breast cancer.
Despite features of aggressiveness, MBC is associated with a favorable prognosis …

This article focuses on the role of Rho family GTPases, particularly Rac1 and Rac1b in TGF‐
β‐induced epithelial‐mesenchymal transition (EMT) and EMT‐associated responses such …

Extracellular matrix proteins control the formation of the inorganic component of hard tissues
including bone, dentin, and enamel. The structural proteins expressed primarily in the …

Disruption of retinoic acid (RA) signaling during early development results in severe
respiratory tract abnormalities, including lung agenesis. Previous studies suggest that this …

Cell morphology dictates response to a wide variety of stimuli, controlling cell metabolism,
differentiation, proliferation, and death. Epithelial‐mesenchymal transition (EMT) is a …

Background Progression of pancreatic ductal adenocarcinoma (PDAC) is largely the result
of genetic and/or epigenetic alterations in the transforming growth factor-beta (TGF-β)/Smad …

Conventional chemotherapy fails to cure metastatic hepatoma mainly due to its high
hepatotoxicity. Many plant-derived agents have been accepted to effectively inhibit …