HIV-1 persists in infected individuals despite years of antiretroviral therapy (ART), due to the
formation of a stable and long-lived latent viral reservoir. Early ART can reduce the latent …

Background HIV-1 produces Tat, a crucial protein for transcription, viral replication, and CNS
neurotoxicity. Tat interacts with TAR, enhancing HIV reverse transcription. Subtype C Tat …

Introduction: Monitoring resistance to first line Antiretroviral therapy (ART) is crucial in
preventing accumulation of viral mutations following the implementation of the World Health …

Currently, HIV-1 displays a substantial level of genetic diversity on a global scale, partly
attributed to its recombinant variants. This study seeks to identify and analyze HIV-1 …

The Sustainable East Africa Research in Community Health (SEARCH) trial was a universal
test-and-treat (UTT) trial in rural Uganda and Kenya, aiming to lower regional HIV-1 …

In recent years, especially as a result of war in Ukraine, enormous movements of migration
to Poland from eastern European countries have been reported, including people living with …

The emergence and spread of new HIV-1 variants pose a challenge for the effectiveness of
antiretrovirals (ARV) targeting Pol proteins. During viral evolution, non-synonymous …

Background The impacts of genetic polymorphisms on drug resistance mutations (DRMs)
among various HIV-1 subtypes have long been debated. In this study, we aimed to analyze …

This study seeks to investigate challenges to combined antiretroviral therapy (cART)
treatment adherence and treatment outcomes in Kampala, Uganda. Data was collected from …

Introducción El VIH/sida es una enfermedad que continúa siendo una amenaza para la
salud pública. Objetivo Estimar la carga de la enfermedad generada por el VIH/sida en los …