Antioxidants in arrhythmia treatment—still a controversy? A review of selected clinical and laboratory research

J Szyller, D Jagielski, I Bil-Lula - Antioxidants, 2022 - mdpi.com
Antioxidants are substances that can prevent damage to cells caused by free radicals.
Production of reactive oxygen species and the presence of oxidative stress play an …

Inactivation of the Ras/MAPK/PPARγ signaling axis alleviates diabetic mellitus-induced erectile dysfunction through suppression of corpus cavernosal endothelial cell …

Z Zhang, HY Zhang, Y Zhang, H Li - Endocrine, 2019 - Springer
Purpose Diabetic mellitus-induced erectile dysfunction (DMED) represents a significant
complication associated with diabetes mellitus (DM) that greatly affects human life quality …

Expanding arsenal against diabetes mellitus through nanoformulations loaded with glimepiride and simvastatin: A comparative study

NK Pandey, SK Singh, B Kumar, M Gulati… - … Science and Pollution …, 2022 - Springer
Type 2 diabetes mellitus is one of the most common and life-threatening diseases found
across the globe. It occurs due to insulin resistance (IR). Major causes of IR include obesity …

Goji Berry (Lycium Barbarum) in the treatment of diabetes mellitus: a systematic review

CS Silva, BCA Alves, LA Azzalis, VBC Junqueira… - 2017 - agris.fao.org
Diabetes Mellitus (DM) is a chronic disease characterized by disorders in the metabolism of
carbohydrates, lipids, lipoproteins and increased oxidative stress. New therapeutic …

Network medicine based approach for identifying the type 2 diabetes, osteoarthritis and triple negative breast cancer interactome: Finding the hub of hub genes

IA Durrani, P John, A Bhatti, JS Khan - Heliyon, 2024 - cell.com
The increasing prevalence of multi-morbidities, particularly the incidence of breast cancer in
diabetic/osteoarthritic patients emphasize on the need for exploring the underlying …

[HTML][HTML] Pleiotropic effects of Salacia reticulata and Simvastatin on oxidative stress and insulin resistance in a rat model

S Gujjala, M Bangeppagari, VLNP Devarakonda… - Biomedicine & …, 2023 - Elsevier
Background The present study investigated the effects of Salacia reticulata and simvastatin
on oxidative stress and insulin resistance in Sprague-Dawley (SD) rats. We compared the …

Simvastatin inhibits epithelial-to-mesenchymal transition through induction of HO-1 in cultured renal proximal tubule cells

JS Clark, AJ Carter, M Dixit, I Arany - in vivo, 2016 - iv.iiarjournals.org
Background/Aim: Studies have shown that simvastatin (SIM) inhibits epithelial-mesenchymal
transition (EMT), a key step in fibrosis, and activates the anti-fibrotic heme oxygenase-1 (HO …

Evaluation of the effects of metformin on antioxidant biomarkers and mineral levels in patients with type II diabetes mellitus: A cross-sectional study

D Manica, G Sandri, GB da Silva, A Manica… - Journal of Diabetes and …, 2023 - Elsevier
Diabetes mellitus (DM) and arterial hypertension are considered serious public health
problems. Several studies have shown that oxidative stress is usually related to the onset of …

[PDF][PDF] The Protective Potential of Tiron in Models of Direct and Physiologically Induced Reactive Oxygen Species

D Meyer - 2019 - pureportal.coventry.ac.uk
Reactive oxygen species (ROS) derived damage and accompanying oxidative stress have
been identified in a number of pathological conditions. As a result, antioxidant …

Association of Simvastatin Use with Glycemic Control in Type 2 Diabetes Patients Receiving Oral Antihyperglycemic Therapy and in Non-Diabetic Subjects

NR Razali - 2018 - search.proquest.com
Previous evidence shows the conflicting effect of simvastatin on glycemic control on type 2
diabetes (T2D) patients. Although the lipid-lowering benefits of simvastatin have been …