Effects of Lipoic Acid on Ischemia‐Reperfusion Injury

Y Ding, Y Zhang, W Zhang, J Shang… - … medicine and cellular …, 2021 - Wiley Online Library
Ischemia‐reperfusion (I/R) injury often occurred in some pathologies and surgeries. I/R
injury not only harmed to physiological functions of corresponding organ and tissue but also …

The complicated role of nuclear factor erythroid-derived 2-like 2 in allergy and asthma

CE Rockwell, Y Jin, AP Boss, LM Kaiser… - Drug Metabolism and …, 2022 - ASPET
Nuclear factor erythroid-derived 2-like 2 (Nrf2) is a stress-activated transcription factor that is
highly responsive to oxidative stress and electrophilic stimuli. Upon activation, Nrf2 …

Quercetin improves the imbalance of Th1/Th2 cells and Treg/Th17 cells to attenuate allergic rhinitis

X Ke, Z Chen, X Wang, H Kang, S Hong - Autoimmunity, 2023 - Taylor & Francis
Allergic rhinitis (AR) is a common inflammation that affects many people globally. Quercetin
has anti-allergic biological activity in AR. Here, we aimed to explore the effects of quercetin …

L-theanine modulates intestine-specific immunity by regulating the differentiation of CD4+ T cells in ovalbumin-sensitized mice

QY Qu, XY Song, L Lin, ZH Gong, W Xu… - Journal of Agricultural …, 2022 - ACS Publications
Ovalbumin (OVA), a common food protein, can cause deadly allergies with intestine-specific
immune reactions. L-Theanine (LTA) shows great potential for regulating intestinal immunity …

Formononetin ameliorates IL‑13‑induced inflammation and mucus formation in human nasal epithelial cells by activating the SIRT1/Nrf2 signaling pathway

J Huang, X Chen, A Xie - Molecular Medicine Reports, 2021 - spandidos-publications.com
Formononetin has proven to be anti‑inflammatory and able to alleviate symptoms of certain
allergic diseases. The present study aimed to determine and elucidate the potential effects …

Immunomodulatory effects of icariin in a myocardial infarction mouse model

X Sai, Z Li, G Deng, L Wang, W Xiaowu, MI Nasser… - …, 2022 - Taylor & Francis
Myocardial infarction (MI) is a prevalent cardiovascular disease defined by myocardial
ischemia and hypoxic damage caused by plaque rupture, thrombosis, lumen stenosis, or …

Mechanism of miR-181a-5p in regulatory T/T-helper 17 immune imbalance and asthma development in mice with allergic rhinitis

R He, Y Chen, X Chen, B Yuan - International Archives of Allergy and …, 2022 - karger.com
Introduction: Allergic rhinitis (AR) is an immune disorder and also a risk factor of asthma.
microRNAs (miRNAs) are implicated in autoimmune diseases, including RA. This study …

Fructus Amomi extract attenuates nasal inflammation by restoring Th1/Th2 balance and down-regulation of NF-κB phosphorylation in OVA-induced allergic rhinitis

Y Fan, TV Nguyen, CH Piao, HS Shin… - Bioscience …, 2022 - portlandpress.com
Abstract Fructus Amomi Cardamomi (FA) is the mature fruit of Amomum villosum Lour (family
Zingiberaceae) and is commonly used in Chinese traditional medicine to treat various …

The effect of icariin on autoimmune premature ovarian insufficiency via modulation of Nrf2/HO-1/Sirt1 pathway in mice

H Chen, L Song, X Xu, Z Han, F Peng, Q Zhang… - Reproductive …, 2022 - Elsevier
abstract Primary ovarian insufficiency (POI) is a common gynecological disease.
Autoimmunity is a common cause of POI. Icariin (ICA) plays a therapeutic role in many …

SymMap database and TMNP algorithm reveal Huanggui Tongqiao granules for Allergic rhinitis through IFN-mediated neuroimmuno-modulation

Y Kong, M Hao, A Chen, T Yi, K Yang, P Li… - Pharmacological …, 2022 - Elsevier
Allergic rhinitis (AR) is a series of reactions to allergen mediated by immunoglobulin E (IgE)
and is one of the most common allergic diseases that affects children. Traditional Chinese …