We have previously described new pathways of vitamin D3 activation by CYP11A1 to
produce a variety of metabolites including 20 (OH) D3 and 20, 23 (OH) 2 D3. These can be …

Basal cell carcinoma (BCC) of the skin is driven by aberrant hedgehog signaling. Thus
blocking this signaling pathway by small molecules such as vismodegib inhibits tumor …

Understanding of cancer with the help of ever-expanding cutting edge technological tools
and bioinformatics is revolutionizing modern cancer research by broadening the space of …

In human skin, keratinopoiesis is based on a functional hierarchy among keratinocytes, with
rare slow-cycling stem cells responsible for the long-term maintenance of the tissue through …

This commentary summarizes studies showing risk of basal cell carcinoma (BCC)
development in relationship to environmental, occupational and therapeutic exposure to …

Development of a head is a dazzlingly complex process: a number of distinct cellular
sources including cranial ecto-and endoderm, mesoderm and neural crest contribute to …

Basal cell carcinoma (BCC) is the most frequently occurring form of all cancers. The cost of
care for BCC is one of the highest for all cancers in the Medicare population in the United …

Chemical warfare agents, particularly vesicants like lewisite, pose a threat due to their ability
to cause skin damage through accidental exposure or deliberate attacks. Lewisite rapidly …

Lewisite is a potent arsenic-based chemical warfare agent known to induce painful
cutaneous inflammation and blistering. Only a few modestly effective antidotes have so far …

Simple Summary In multicellular organisms, inflammation is the body's most primitive and
essential protective response against any external agent. Inflammation, however, not only …