Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …

Proteins carry out a wide variety of catalytic, regulatory, signalling and structural functions in
living systems. Following their assembly on ribosomes and throughout their lifetimes, most …

Glycosylation is one of the most prevalent posttranslational modifications that profoundly
affects the structure and functions of proteins in a wide variety of biological recognition …

The translation of biological glycosylation in humans to the clinical applications involves
systematic studies using homogeneous samples of oligosaccharides and glycoconjugates …

Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

Glycoconjugates are the ubiquitous components of mammalian cells, mainly synthesized by
covalent bonds of carbohydrates to other biomolecules such as proteins and lipids, with a …

The N-glycans attached to the Fab and Fc domains play distinct roles in modulating the
functions of antibodies. However, posttranslational site-selective modifications of glycans in …

At present, nearly 70% of recombinant therapeutic proteins (RTPs) are produced by Chinese
hamster ovary (CHO) cells, and serum-free medium (SFM) is necessary for their culture to …

The many advances in glycoscience have more and more brought to light the crucial role of
glycosides and glycoconjugates in biological processes. Their major influence on the …

Cell surfaces are glycosylated in various ways with high heterogeneity, which usually leads
to ambiguous conclusions about glycan-involved biological functions. Here, we describe a …