Copper is an essential micronutrient for both pathogens and the animal hosts they infect.
However, copper can also be toxic in cells due to its redox properties and ability to disrupt …

Copper is a ubiquitous element in the environment as well as living organisms, with its redox
capabilities and complexation potential making it indispensable for many cellular functions …

The primary objective of the present study was to examine the influence of early systemic
toxicity resulting from copper (Cu) exposure on metamorphic processes in Xenopus laevis. A …

With the emerging primary resistance of Mycobacterium tuberculosis to current drugs and
wide distribution of latent tuberculosis infection, the need for new compounds with a novel …

The acquisition and storage of metals has been a preoccupation of life for millennia.
Transition metals, in particular iron, copper and zinc, have vital roles within cells. However …

Iron and copper chelation restricts Plasmodium growth in vitro and in mammalian hosts. The
parasite alters metal homeostasis in red blood cells to its favor, for example metabolizing …

Background Malaria-associated acute lung injury/acute respiratory distress syndrome (MA-
ALI/ARDS) is a fatal complication of Plasmodium falciparum infection that is partially …

Background The unmet demand for effective malaria transmission-blocking agents targeting
the transmissible stages of Plasmodium necessitates intensive discovery efforts. In this …

Copper can exist in an oxidized and a reduced form, which enables the metal to play
essential roles as a catalytic co-factor in redox reactions in many organisms. Copper confers …

Copper (Cu) is an essential micronutrient for all aerobic forms of life. Its oxidation states
(Cu+/Cu2+) make this metal an important cofactor of enzymes catalyzing redox reactions in …