Virulence of the zoonotic agent of leptospirosis: still terra incognita?

M Picardeau - Nature Reviews Microbiology, 2017 - nature.com
Pathogenic leptospires are the bacterial agents of leptospirosis, which is an emerging
zoonotic disease that affects animals and humans worldwide. The success of leptospires as …

A systematic review of Leptospira in water and soil environments

E Bierque, R Thibeaux, D Girault, ME Soupé-Gilbert… - PloS one, 2020 - journals.plos.org
Background Leptospirosis, caused by pathogenic Leptospira, is a zoonosis of global
distribution. This infectious disease is mainly transmitted by indirect exposure to urine of …

Leptospirosis and the environment: A review and future directions

EA Bradley, G Lockaby - Pathogens, 2023 - mdpi.com
Leptospirosis is a zoonotic disease of global importance with significant morbidity and
mortality. However, the disease is frequently overlooked and underdiagnosed, leading to …

A global one health perspective on leptospirosis in humans and animals

JE Sykes, DA Haake, CD Gamage… - Journal of the …, 2022 - Am Vet Med Assoc
Leptospirosis is a quintessential one health disease of humans and animals caused by
pathogenic spirochetes of the genus Leptospira. Intra-and interspecies transmission is …

Critical knowledge gaps in our understanding of environmental cycling and transmission of Leptospira spp

V Barragan, S Olivas, P Keim… - Applied and …, 2017 - Am Soc Microbiol
Exposure to soil or water contaminated with the urine of Leptospira-infected animals is the
most common way in which humans contract leptospirosis. Entire populations can be at high …

Leptospirosis: toward a better understanding of the environmental lifestyle of Leptospira

G Davignon, J Cagliero, L Guentas, E Bierque… - Frontiers in …, 2023 - frontiersin.org
Leptospira is a complex bacterial genus which biodiversity has long been overlooked. In the
recent years however, environmental studies have contributed to shed light on its original …

Leptospirosis and coinfection: should we be concerned?

A Md-Lasim, FS Mohd-Taib, M Abdul-Halim… - International journal of …, 2021 - mdpi.com
Pathogenic Leptospira is the causative agent of leptospirosis, an emerging zoonotic disease
affecting animals and humans worldwide. The risk of host infection following interaction with …

Infectious uveitis in horses and new insights in its leptospiral biofilm-related pathogenesis

B Wollanke, H Gerhards, K Ackermann - Microorganisms, 2022 - mdpi.com
Uveitis is a sight-threatening eye disease in equids known worldwide that leads to
considerable pain and suffering. By far the most common type of uveitis in Germany and …

Environmental Biofilms from an Urban Community in Salvador, Brazil, Shelter Previously Uncharacterized Saprophytic Leptospira

P dos Santos Ribeiro, NB Carvalho, F Aburjaile… - Microbial Ecology, 2023 - Springer
Biofilms are complex microecosystems with valuable ecological roles that can shelter a
variety of microorganisms. Spirochetes from the genus Leptospira have been observed to …

The zoonotic pathogen Leptospira interrogans mitigates environmental stress through cyclic-di-GMP-controlled biofilm production

R Thibeaux, ME Soupé-Gilbert, M Kainiu… - npj Biofilms and …, 2020 - nature.com
The zoonotic bacterium Leptospira interrogans is the aetiological agent of leptospirosis, a re-
emerging infectious disease that is a growing public health concern. Most human cases of …