Nasopharyngeal carcinoma: an evolving paradigm

KCW Wong, EP Hui, KW Lo, WKJ Lam… - Nature reviews Clinical …, 2021 - nature.com
The past three decades have borne witness to many advances in the understanding of the
molecular biology and treatment of nasopharyngeal carcinoma (NPC), an Epstein–Barr virus …

Volumetric modulated arc therapy (VMAT): a review of clinical outcomes—what is the clinical evidence for the most effective implementation?

SO Hunte, CH Clark, N Zyuzikov… - The British Journal of …, 2022 - academic.oup.com
Modern conformal radiation therapy using techniques such as modulation, image guidance
and motion management have changed the face of radiotherapy today offering superior …

Squamous cell carcinoma of the oral cavity, larynx, oropharynx and hypopharynx: EHNS–ESMO–ESTRO Clinical Practice Guidelines for diagnosis, treatment and …

JP Machiels, CR Leemans, W Golusinski… - Annals of …, 2020 - annalsofoncology.org
Squamous cell carcinoma of the head and neck (SCCHN) arises from epithelial cells and
occurs in the oral cavity, pharynx and larynx. Nasopharyngeal carcinoma (NPC) is a disease …

Osteoradionecrosis of the jaw following proton radiation therapy for patients with head and neck cancer

A Singh, S Kitpanit, B Neal, E Yorke… - … –Head & Neck …, 2023 - jamanetwork.com
Importance Proton radiation therapy (PRT) has reduced radiation-induced toxic effects, such
as mucositis and xerostomia, over conventional photon radiation therapy, leading to …

Toxicity profiles and survival outcomes among patients with nonmetastatic nasopharyngeal carcinoma treated with intensity-modulated proton therapy vs intensity …

X Li, S Kitpanit, A Lee, D Mah, K Sine… - JAMA Network …, 2021 - jamanetwork.com
Importance Patients with nonmetastatic nasopharyngeal carcinoma (NPC) are primarily
treated by radiotherapy with curative intent with or without chemotherapy and often …

Intensity-modulated radiation therapy versus three-dimensional conformal radiotherapy in head and neck squamous cell carcinoma: long-term and mature outcomes …

T Gupta, S Sinha, S Ghosh-Laskar, A Budrukkar… - Radiation …, 2020 - Springer
Purpose To compare long-term disease-related outcomes and late radiation morbidity
between intensity-modulated radiation therapy (IMRT) and three-dimensional conformal …

Endogenous stimuli-responsive nanoparticles for cancer therapy: from bench to bedside

F Xie, M Wang, Q Chen, T Chi, S Zhu, P Wei… - Pharmacological …, 2022 - Elsevier
Cancer is complicated to treat because of its high propensity for recurrence and metastasis,
and various side effects of conventional cancer treatments. With the development of …

Anatomic changes in head and neck intensity-modulated proton therapy: Comparison between robust optimization and online adaptation

A Lalonde, M Bobić, B Winey, J Verburg… - Radiotherapy and …, 2021 - Elsevier
Background/purpose Setup variations and anatomical changes can severely affect the
quality of head and neck intensity-modulated proton therapy (IMPT) treatments. The impact …

The first PET glimpse of a proton FLASH beam

F Abouzahr, JP Cesar, P Crespo, M Gajda… - Physics in Medicine …, 2023 - iopscience.iop.org
We demonstrate the first ever recorded positron-emission tomography (PET) imaging and
dosimetry of a FLASH proton beam at the Proton Center of the MD Anderson Cancer Center …

The current status of FLASH particle therapy: a systematic review

J Atkinson, E Bezak, H Le, I Kempson - Physical and Engineering …, 2023 - Springer
Particle therapies are becoming increasingly available clinically due to their beneficial
energy deposition profile, sparing healthy tissues. This may be further promoted with ultra …