[HTML][HTML] Acyl-CoA: diacylglycerol acyltransferase: Properties, physiological roles, metabolic engineering and intentional control

G Chen, JL Harwood, MJ Lemieux, SJ Stone… - Progress in Lipid …, 2022 - Elsevier
Acyl-CoA: diacylglycerol acyltransferase (DGAT, EC 2.3. 1.20) catalyzes the last reaction in
the acyl-CoA-dependent biosynthesis of triacylglycerol (TAG). DGAT activity resides mainly …

Cationic Lignin as an Efficient and Biorenewable Antimicrobial Material

K Acurio Cerda, M Kathol, G Purohit… - ACS Sustainable …, 2023 - ACS Publications
In this work, we utilized an inexpensive and naturally abundant polymer lignin and
functionalized it with quaternary ammonium groups to yield a cationic antimicrobial, QAL. As …

Stepwise metabolic engineering of Escherichia coli to produce triacylglycerol rich in medium-chain fatty acids

L Xu, L Wang, XR Zhou, WC Chen, S Singh… - Biotechnology for …, 2018 - Springer
Abstract Background Triacylglycerols (TAGs) rich in medium-chain fatty acids (MCFAs, C10–
14 fatty acids) are valuable feedstocks for biofuels and chemicals. Natural sources of TAGs …

Crystal Structure of the Bifunctional Wax Synthase 1 from Acinetobacter baylyi Suggests a Conformational Change upon Substrate Binding and Formation of …

K Vollheyde, K Kühnel, F Lambrecht, S Kawelke… - ACS …, 2022 - ACS Publications
Wax esters (WE) are neutral lipids that are formed by the transesterification of an activated
fatty acyl moiety to a fatty alcohol. Due to their diverse physicochemical properties, WE are …

Cationic π-conjugated polyelectrolyte shows antimicrobial activity by causing lipid loss and lowering elastic modulus of bacteria

E Zamani, TJ Johnson, S Chatterjee… - … applied materials & …, 2020 - ACS Publications
Cationic, π-conjugated oligo-/polyelectrolytes (CCOEs/CCPEs) have shown great potential
as antimicrobial materials to fight against antibiotic resistance. In this work, we treated wild …

The phospholipid: diacylglycerol acyltransferase-mediated acyl-coenzyme A-independent pathway efficiently diverts fatty acid flux from phospholipid into …

L Wang, S Jiang, WC Chen, XR Zhou… - Applied and …, 2020 - Am Soc Microbiol
Researchers have long endeavored to accumulate triacylglycerols (TAGs) or their
derivatives in easily managed microbes. The attempted production of TAGs in Escherichia …

Directed evolution of a bacterial WS/DGAT acyltransferase: improving tDGAT from Thermomonospora curvata

O Santín, S Galié, G Moncalián - Protein Engineering, Design …, 2019 - academic.oup.com
Some bacteria belonging to the actinobacteria and proteobacteria groups can accumulate
neutral lipids expressing enzymes of the wax ester synthase/acyl coenzyme A …

Production of halogenated indigo by Escherichia coli whole-cell conversion system with novel halogenase derived from Pseudoalteromonas nigrifaciens

B Yi, BW Lee, K Yu, HG Koh, YH Yang, KY Choi… - Biotechnology and …, 2024 - Springer
Indigo is a commercially significant dye extensively used in the textile industry for dyeing
denim and other fabrics. The synthesis of various colored indigo derivatives necessitates the …

The Fifth WS/DGAT Enzyme of the Bacterium Marinobacter aquaeolei VT8

K Vollheyde, D Yu, E Hornung, C Herrfurth, I Feussner - Lipids, 2020 - Wiley Online Library
Wax esters (WE) belong to the class of neutral lipids. They are formed by an esterification of
a fatty alcohol and an activated fatty acid. Dependent on the chain length and desaturation …

脂肪酸延长酶缺陷对酵母细胞脂质代谢及油酸胁迫响应的影响

程迅, 杜秀秀, 王寒冬, 黄志伟, 邓云霞, 沈裕虎 - 2018 - ir.nwipb.ac.cn
摘要生物医学证据表明, 过量的油脂特别是脂肪酸(fatty acids, FA) 在非脂肪组织累积会引起脂
代谢障碍, 引起细胞功能紊乱或坏死. 脂肪酸延长酶家族参与脂肪酸代谢, 具有真核生物的高度 …