There is a high demand for new drugs against malaria, which takes millions of lives
annually. The abuse of classical antimalarials from the late 1940's to the early 1980's has …

Background Artesunate-sulfadoxine-pyrimethamine (ASSP) is the frontline artemisinin
combination therapy (ACT) in India. Random, irrational, subtherapeutic artemisinin doses …

Abstract Objectives Human Plasmodium knowlesi infections have been reported from
several South-East Asian countries, excluding India, but its drug susceptibility profile in …

The malaria parasite has been allowed to get perilously close to winning the upper hand in
the race between new drugs and resistance development. Today, just one class of drugs is …

Chloroquine (CQ) is officially used for the primary treatment of Plasmodium falciparum
malaria in Honduras. In this study, the therapeutic efficacy of CQ for the treatment of …

Background Sulfadoxine-pyrimethamine (SP) combination drug is currently being used in
India for the treatment of Plasmodium falciparum as partner drug in artemisinin-based …

Introduction After being used vigorously for the previous two decades to treat P. falciparum,
chloroquine and sulfadoxine-pyrimethamine were replaced in 2009 with an artemisinin …

Objectives Drug resistance in parasitic protozoa is an obstacle to successful chemotherapy.
Understanding how pathogens respond to drugs is crucial in preventing resistance …

Drug-resistant Plasmodium falciparum parasite poses a great problem for the malaria
control programme of any country. The most commonly used antimalarial drugs, viz …

Background Artesunate+ sulphadoxine-pyrimethamine (AS+ SP) is recommended
throughout India as the first-line treatment for uncomplicated falciparum malaria. Due to the …