Machine learning for the advancement of genome-scale metabolic modeling

P Kundu, S Beura, S Mondal, AK Das, A Ghosh - Biotechnology Advances, 2024 - Elsevier
Constraint-based modeling (CBM) has evolved as the core systems biology tool to map the
interrelations between genotype, phenotype, and external environment. The recent …

Bayesian 13C-Metabolic Flux Analysis of Parallel Tracer Experiments in Granulocytes: A Directional Shift within the Non-Oxidative Pentose Phosphate Pathway …

M Hogg, EM Wolfschmitt, U Wachter, F Zink… - Metabolites, 2023 - mdpi.com
The pentose phosphate pathway (PPP) plays a key role in the cellular regulation of immune
function; however, little is known about the interplay of metabolic adjustments in …

[HTML][HTML] CFSA: Comparative flux sampling analysis as a guide for strain design

RP van Rosmalen, S Moreno-Paz… - Metabolic Engineering …, 2024 - Elsevier
Genome-scale metabolic models of microbial metabolism have extensively been used to
guide the design of microbial cell factories, still, many of the available strain design …

[PDF][PDF] Applications of Vertex and Edge Labeling in Computational Biology

M Sindhu, M Kannan - researchgate.net
In this study, two basic labeling techniques, namely vertex and edge labeling techniques are
investigated for their use in computational biology particularly in the solution of protein …