The redox-active protein cytochrome c is a highly positively charged hemoglobin that
regulates cell fate decisions of life and death. Under normal physiological conditions …

Covering: up to 2023 Infusions of the plants Artemisia annua and A. afra are gaining broad
popularity to prevent or treat malaria. There is an urgent need to address this controversial …

In situ-activated therapy is a decent option for localized diseases with improved efficacies
and reduced side effects, which is heavily dependent on the local conversion or activation of …

Polycystic ovary syndrome (PCOS), a prevalent reproductive disorder in women of
reproductive age, features androgen excess, ovulatory dysfunction, and polycystic ovaries …

A novel polysaccharide PSP2-1 was isolated and purified from Pleurotus sajor-caju. The
structural characterization data displayed that the molecular weight of PSP2-1 was 44.9 kDa …

Porcine reproductive and respiratory syndrome virus (PRRSV) causes significant economic
losses to the pork industry worldwide. Currently, vaccine strategies provide limited protection …

Artemisinin-based combination therapies (ACT) are the frontline treatments against malaria
worldwide. Recently the use of traditional infusions from Artemisia annua (from which …

Oral squamous cell carcinoma (OSCC), with aggressive locoregional invasion, has a high
rate of early recurrences and poor prognosis. Dihydroartemisinin (DHA), as a derivative of …

The action mechanisms of artemisinins remains elusive for decades, and one long-standing
question is whether the indispensable peroxide group is activated by iron or heme. Although …

Ferroptosis is a newly detected iron-dependent form of regulated cell death. Sono-
photodynamic therapy (SPDT) can generate reactive oxygen species (ROS) and induce cell …