Improvements in both liquid chromatography (LC) and mass spectrometry (MS)
instrumentation have greatly enhanced proteomic and small molecule metabolomic analysis …

Chronic obstructive pulmonary disease (COPD) patients frequently suffer from multiple
comorbidities, resulting in poor outcomes for these patients. Diabetes is observed at a …

Urinary peptides gained significant attention as potential biomarkers especially in the
context of kidney and cardiovascular disease. In this manuscript the recent literature since …

Chronic kidney disease (CKD) is a non-specific type of kidney disease that causes a gradual
decline in kidney function (from months to years). CKD is a significant risk factor for death …

Biomarker development, improvement, and clinical implementation in the context of kidney
disease have been a central focus of biomedical research for decades. To this point, only …

Abstract Alpha-1 antitrypsin (A1AT) is a protease inhibitor in the serum. Its primary function is
to inhibit the activity of a series of proteases, including proteinase 3, neutrophil elastase …

Biomedicine is developing rapidly in the 21st century. Among them, the qualitative and
quantitative analysis of peptide biomarkers is of considerable importance for the diagnosis …

Alpha-1 antitrypsin (AAT) has established anti-inflammatory and immunomodulatory effects
in chronic obstructive pulmonary disease but there is increasing evidence of its role in other …

The cardiorenal syndrome (CRS) is defined as the confluence of heart-kidney dysfunction.
This study investigates the molecular differences at the level of the urinary peptidome …

Traumatic brain injury (TBI) is a multidimensional damage, and currently, no FDA-approved
medicine is available. Multiple pathways in the cell are triggered through a head injury (eg …