Nowadays, diabetes and obesity are two main health-threatening metabolic disorders in the
world, which increase the risk for many chronic diseases. Apelin, a peptide hormone, exerts …

Obesity, a pandemic disease, is caused by an excessive accumulation of fat that can have
detrimental effects on health. Adipose tissue plays a very important endocrine role, secreting …

Adipose tissue (AT) is one of the largest endocrine organs contributing to metabolic
homeostasis. The functional pleiotropism of AT depends on its ability to secrete a large …

Abstract Purpose of Review In this review, we investigate the role of classic and novel
adipocytokines in cancer pathogenesis synopsizing the mechanisms underlying the …

The G protein-coupled receptor APJ and its cognate ligand, apelin, are widely expressed
throughout human body. They are implicated in different key physiological processes such …

Apelin, a peptide with several active isoforms ranging from 36 to 12 amino acids and its
receptor APJ, a G-protein-coupled receptor, are widely distributed. However, apelin has …

Context Apelin is an adipokine expressed in several tissues and it appears to be involved in
energy metabolism. Objective The aim of this study was to determine serum apelin levels in …

Introduction: Apelin, a bioactive peptide, is the endogenous ligand of APJ, a G protein-
coupled receptor which is widely expressed in peripheral tissues and in the central nervous …

Type 2 diabetes mellitus (T2DM) is a metabolic disorder associated with abundant
adipocytokine changes which may play an important role in the progression of insulin …

Obesity is a constantly growing health problem which reduces quality of life and life
expectancy. Bariatric surgery (BS) for obesity is considered when all other conservative …