Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy

CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

Curcumin and cancer

A Giordano, G Tommonaro - Nutrients, 2019 - mdpi.com
Curcumin, a polyphenol extracted from Curcuma longa in 1815, has gained attention from
scientists worldwide for its biological activities (eg, antioxidant, anti-inflammatory …

Phytosomal curcumin: A review of pharmacokinetic, experimental and clinical studies

H Mirzaei, A Shakeri, B Rashidi, A Jalili… - Biomedicine & …, 2017 - Elsevier
Curcumin, a hydrophobic polyphenol, is the principal constituent extracted from dried
rhizomes of Curcuma longa L.(turmeric). Curcumin is known as a strong anti-oxidant and …

Advances in nanoparticle and microparticle delivery systems for increasing the dispersibility, stability, and bioactivity of phytochemicals

DJ McClements - Biotechnology advances, 2020 - Elsevier
Application of bioactive phytochemicals in foods, supplements, and pharmaceuticals is often
limited because of their poor solubility, stability, and bioavailability. Phytochemical oral …

Nanotechnology for angiogenesis: opportunities and challenges

S Kargozar, F Baino, S Hamzehlou… - Chemical Society …, 2020 - pubs.rsc.org
Angiogenesis plays a critical role within the human body, from the early stages of life (ie,
embryonic development) to life-threatening diseases (eg, cancer, heart attack, stroke, wound …

Exosomes for the enhanced tissue bioavailability and efficacy of curcumin

F Aqil, R Munagala, J Jeyabalan, AK Agrawal… - The AAPS journal, 2017 - Springer
Exosomes are extracellular microvesicles with a particle size of 30–100 nm and carry a
cargo of proteins, lipids, RNA, and DNA. Their properties of shuttling in-and-out of the cells …

A review on drug delivery system for tumor therapy

G Liu, L Yang, G Chen, F Xu, F Yang, H Yu… - Frontiers in …, 2021 - frontiersin.org
In recent years, with the development of nanomaterials, the research of drug delivery
systems has become a new field of cancer therapy. Compared with conventional antitumor …

Designing a broad-spectrum integrative approach for cancer prevention and treatment

KI Block, C Gyllenhaal, L Lowe, A Amedei… - Seminars in cancer …, 2015 - Elsevier
Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …

Anticancer properties of curcumin against colorectal cancer: a review

OA Ojo, TR Adeyemo, D Rotimi, GES Batiha… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is one of the most common and reoccurring diseases, as well as
the world's second largest cause of mortality. Despite existing preventative, diagnostic, and …

Nanodelivery of dietary polyphenols for therapeutic applications

M Rudrapal, AK Mishra, L Rani, KK Sarwa… - Molecules, 2022 - mdpi.com
Advancement in nanotechnology has unleashed the therapeutic potentials of dietary
polyphenols by enhancing bioavailability, improving biological half-life, and allowing site …