We present a major update of the HOCOMOCO collection that provides DNA binding
specificity patterns of 949 human transcription factors and 720 mouse orthologs. To make …

Currently, numerous associations between genetic polymorphisms and various diseases
have been characterized through the Genome-Wide Association Studies. Majority of the …

There is growing evidence that a wide range of human diseases and physiological traits are
influenced by genetic variation of cis-regulatory elements. We and others have shown that a …

Genome-wide association studies (GWAS) have mapped over 90% of disease-and
quantitative-trait-associated variants within the non-coding genome. Non-coding regulatory …

Genome-wide association studies along with expression quantitative trait locus (eQTL)
mapping have identified hundreds of single-nucleotide polymorphisms (SNPs) and their …

Here we present a comprehensive HiChIP dataset on naïve CD4 T cells (nCD4) from 30
donors and identify QTLs that associate with genotype-dependent and/or allele-specific …

Single-nucleotide polymorphism rs71327024 located in the human 3p21. 31 locus has been
associated with an elevated risk of hospitalization upon SARS-CoV-2 infection. The 3p21 …

The role of host genetic factors in COVID-19 outcomes remains unclear despite various
genome-wide association studies (GWAS). We annotate all significant variants and those …

The goal of our study was to identify and assess the functionally significant SNPs with
potentially important roles in the development of type 2 diabetes mellitus (T2DM) and/or their …

Bioinformatics has become an interdisciplinary subject due to its universal role in molecular
biology research. The current status of Russia's bioinformatics research in Russia is not …