Simple Summary Tumor stroma is known to significantly influence cancer initiation and
progression. In the last decade, 3D cell cultures have shown potential in modeling the tumor …

Extracellular matrix (ECM)-mimicking biomaterials are considered effective tissue-
engineered scaffolds for regenerative medicine because of their biocompatibility …

Distinct anti-inflammatory macrophage (M2) subtypes, namely M2a and M2c, are reported to
modulate the tissue repair process tightly and chronologically by modulating fibroblast …

Collagen alignment is one of the key microarchitectural signatures of many pathological
conditions, including scarring and fibrosis. Investigating how collagen alignment modulates …

All terrestrial organisms have evolved and adapted to thrive under Earth's gravitational force.
Due to the increase of crewed space flights in recent years, it is vital to understand how the …

During tumor growth the extracellular matrix (ECM) undergoes dramatic remodeling. The
normal ECM is degraded and substituted with a tumor-specific ECM, which is often of higher …

Atherosclerosis is a chronic inflammatory disease characterized by lipid accumulation and
plaque formation in arterial vessel walls. Atherosclerotic plaques narrow the arterial lumen …

The increasing use of medical implants in various areas of medicine, particularly in
orthopedic surgery, oncology, cardiology and dentistry, displayed the limitations in long-term …

In older individuals, hypertrophy from progressive resistance training (PRT) is compromised
in approximately one-third of participants in exercise trials. The objective of this study was to …

The preconditioning of mesenchymal stem cells (MSCs) has been recognized as an
attractive tool to improve their regenerative and immunomodulatory capacities based on …