The future of canine glaucoma therapy

AM Komáromy, D Bras, DW Esson… - Veterinary …, 2019 - Wiley Online Library
Canine glaucoma is a group of disorders that are generally associated with increased
intraocular pressure (IOP) resulting in a characteristic optic neuropathy. Glaucoma is a …

Changes of visual pathway and brain connectivity in glaucoma: a systematic review

R Nuzzi, L Dallorto, T Rolle - Frontiers in Neuroscience, 2018 - frontiersin.org
Background: Glaucoma is a leading cause of irreversible blindness worldwide. The
increasing interest in the involvement of the cortical visual pathway in glaucomatous patients …

[HTML][HTML] Efficacy and safety of prostaglandin analogues in primary open-angle glaucoma or ocular hypertension patients: a meta-analysis

W Tang, F Zhang, K Liu, X Duan - Medicine, 2019 - journals.lww.com
Background: To evaluated and compared the efficacy and safety of 3 prostaglandin
analogues (0.005% latanoprost, 0.004% travoprost, and 0.03% bimatoprost) in treatment of …

Microglial extracellular vesicles as vehicles for neurodegeneration spreading

ID Aires, T Ribeiro-Rodrigues, R Boia… - Biomolecules, 2021 - mdpi.com
Microglial cells are the neuroimmune competent cells of the central nervous system. In the
adult, microglia are responsible for screening the neuronal parenchyma searching for …

The role of lamina cribrosa tissue stiffness and fibrosis as fundamental biomechanical drivers of pathological glaucoma cupping

AA Hopkins, R Murphy, M Irnaten… - … of Physiology-Cell …, 2020 - journals.physiology.org
The primary biomechanical driver of pathological glaucomatous cupping remains unknown.
Finite element modeling indicates that stress and strain play key roles. In this article …

Timolol-eluting graphene oxide laden silicone contact lens: Control release profile with improved critical lens properties

FA Maulvi, PA Kanani, HJ Jadav, BV Desai… - Journal of Drug Delivery …, 2022 - Elsevier
Glaucoma is a chronic ocular disease characterized by increase in intraocular pressure
(IOP). Currently, it is managed by high drug concentration eye drop solutions. The dosage …

Glaucoma, Pseudoexfoliation and Hearing Loss: A Systematic Literature Review

LA Meliante, G Piccotti, L Tanga, S Giammaria… - Journal of Clinical …, 2024 - mdpi.com
Purpose: To investigate the relationship between glaucoma, pseudoexfoliation and hearing
loss (HL). Methods: A systematic literature search following PRISMA guidelines was …

Rational basis for nutraceuticals in the treatment of glaucoma

ML Antonio, R Laura, A Annagrazia… - Current …, 2018 - ingentaconnect.com
Background: Glaucoma, the second leading cause of blindness worldwide, is a chronic optic
neuropathy characterized by progressive retinal ganglion cell (RGC) axons degeneration …

Down-regulated miR-187 promotes oxidative stress-induced retinal cell apoptosis through P2X7 receptor

QL Zhang, W Wang, ZJ Lu, LL Li, TZ Zhang - International journal of …, 2018 - Elsevier
Several microRNAs (miRNAs) expressed in the retina were confirmed to involve in retinal
cell apoptosis, which was closely linked with the development of retinal diseases. Our …

Prophylactic anti‐glaucoma therapy in dogs with primary glaucoma: A practitioner survey of current medical protocols

CE Plummer, D Bras, S Grozdanic… - Veterinary …, 2021 - Wiley Online Library
Aim To examine the use of prophylactic anti‐glaucoma medications in the normotensive
fellow eye in dogs with unilateral overt primary glaucoma by veterinary ophthalmology …