Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

As a result of ischemia or hemorrhage, blood supply to neurons is disrupted which
subsequently promotes a cascade of pathophysiological responses resulting in cell loss …

The intrinsic ability of neurogenesis after stroke has been proven weak, which results in
insufficient repair of injury in the nerve system. Recent studies suggest multiple microRNAs …

Epigenetic mechanisms—including DNA methylation, histone post-translational
modifications and changes in nucleosome positioning—regulate gene expression, cellular …

Tissue regeneration by stem cells is driven by the paracrine activity of shedding vesicles and
exosomes, which deliver specific cargoes to the recipient cells. Proteins, RNA, cytokines and …

Alzheimer's disease (AD) is a multifaceted, advancing neurodegenerative illness that is
responsible for most cases of neurological impairment and dementia in the aged population …

Background Synaptic loss is an early pathological event in Alzheimer's disease (AD), but its
underlying molecular mechanisms remain largely unknown. Recently, microRNAs (miRNAs) …

Parkinson's disease is a neurodegenerative disease characterized by the loss of
dopaminergic neurons in the substantia nigra with no effective cure available. MicroRNA …

MicroRNA-124 (miR-124) is the most abundant miRNA in the brain. Biogenesis of miR-124
displays specific temporal and spatial profiles in various cell and tissue types and affects a …

The abilities of stem cells to self-renew and form different mature cells expand the
possibilities of applications in cell-based therapies such as tissue recomposition in …