Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

Transplantation of adipose-derived mesenchymal stem cells (ASCs) induces tissue
regeneration by accelerating the growth of blood vessels and nerve. However, mechanisms …

Mesenchymal stem cells (MSCs) have been used for cell-based therapies in regenerative
medicine, with increasing importance in central and peripheral nervous system repair …

Due to the limited regenerative ability of neural tissue, a diverse set of biochemical and
biophysical cues for increasing nerve growth has been investigated, including neurotrophic …

Nerve regeneration remains a difficult challenge due to the lack of safe and efficient matrix
support. We designed a laminin (LN)-modified chitosan multi-walled nerve conduit …

Platelet-rich plasma (PRP) has been tested in vitro, in animal models, and clinically for its
efficacy in enhancing the rate of wound healing, reducing pain associated with injuries, and …

Despite the fact that the peripheral nervous system is able to regenerate after traumatic
injury, the functional outcomes following damage are limited and poor. Bone marrow …

Restoring neurological function to a damaged peripheral nerve separated by a gap requires
axon regeneration (1) across the gap, no matter its length, and then (2) through the distal …

Since several years, adult/perinatal mesenchymal and neural crest stem cells have been
widely used to help experimental animal to recover from spinal cord injury. More …