Beneficial effect of botulinum toxin A on Raynaud's phenomenon in Japanese patients with systemic sclerosis: a prospective, case series study

S Motegi, K Yamada, S Toki… - The Journal of …, 2016 - Wiley Online Library
Currently, there is no satisfactory treatment for Raynaud's phenomenon (RP) in systemic
sclerosis (SS c). Recently, it has been reported that botulinum toxin A (BTX‐A) injection was …

The safety and efficacy of botulinum toxin for management of scars: A systematic review with meta-analysis and trial sequential analysis

D Wang, J Qu, H Jiang, Y Jiang - Toxicon, 2019 - Elsevier
Scars can have a dramatic impact on patients' physical appearance and function. Injection of
botulinum toxin has been used to prevent scar formation at the site of injury and to remodel …

The use of botulinum toxin in flap surgery: a review of the literature

F Segreto, GF Marangi, M Signoretti… - Surgical …, 2019 - journals.sagepub.com
Botulinum neurotoxin-A and botulinum neurotoxin-B have been shown to play a potential
role in improving flap survival in animal models. The aim of this study is to review indications …

Botulinum toxin type A and the prevention of hypertrophic scars on the maxillofacial area and neck: a meta-analysis of randomized controlled trials

D Zhang, X Liu, W Xiao, Y Xu - PLoS One, 2016 - journals.plos.org
Background The purpose of the meta-analysis was to evaluate the efficiency of therapeutic
botulinum toxin type A (BTX-A) in the prevention of maxillofacial and neck scars. Methods …

Protective effect of botulinum toxin A after cutaneous ischemia-reperfusion injury

A Uchiyama, K Yamada, B Perera, S Ogino… - Scientific reports, 2015 - nature.com
Abstract Botulinum toxin A (BTX-A) blocks the release of acetylcholine vesicles into the
synaptic space and has been clinically used for aesthetic indications, neuromuscular …

Visualizing the pharmacologic preconditioning effect of botulinum toxin type A by infrared thermography in a rat pedicled perforator island flap model

M Chen, X Li, Z Jiang, X Gong - Plastic and reconstructive surgery, 2019 - journals.lww.com
Background: Surgical delay can improve flap viability, leading to vasodilation,
neovascularization, and vessel reorganization. Experiments suggest a similar positive effect …

Presurgical botulinum toxin a treatment increases angiogenesis by hypoxia-inducible factor-1α/vascular endothelial growth factor and subsequent superiorly based …

TH Park, SH Lee, YJ Park, YS Lee, DK Rah… - Annals of plastic …, 2016 - journals.lww.com
To date, there have been several experimental studies to assess tissue viability of
transverse rectus abdominis myocutaneous (TRAM) flaps. Botulinum toxin A (BoTA) has …

Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: possible regulation of oxidative and endoplasmic …

A Sekiguchi, S Motegi, A Uchiyama, A Uehara… - Journal of …, 2018 - Elsevier
Background We previously identified that botulinum toxin A (BTX-A) suppressed pressure
ulcer (PU) formation after cutaneous ischemia-reperfusion (I/R) injury; however, regulation of …

Increasing the survival of transverse rectus abdominis musculocutaneous flaps with a Botulinum toxin-A injection: A comparison of surgical and chemical flap delay …

G Temiz, N Yeşiloğlu, H Şirinoğlu, AC Akpınar… - Journal of Plastic …, 2016 - Elsevier
Background Botulinum toxin type-A (Bot-A) is a commonly used drug for both cosmetic and
therapeutic purposes. The effects of Bot-A on skin and muscle flaps and the related …

The protective effects of botulinum toxin a against flap necrosis after perforator twisting and its underlying molecular mechanism in a rat model

SY Kim, SH Lee, B Lee, YJ Park, JH Park… - Annals of plastic …, 2016 - journals.lww.com
Purpose The purpose of this study was to examine our hypotheses that botulinum toxin A
(BoTA) protect necrosis of perforator flap from perforator twisting. Methods Twenty-four rats …