From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer

MS Hussain, ASA Altamimi, M Afzal, I Kazmi… - … -Research and Practice, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …

PVT1 lncRNA in lung cancer: A key player in tumorigenesis and therapeutic opportunities

MA Hakami, A Hazazi, FR Khan, O Abdulaziz… - … -Research and Practice, 2024 - Elsevier
The lncRNA PVT1 has emerged as a pivotal component in the intricate landscape of cancer
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …

18-β-Glycyrrhetinic acid encapsulated PLGA nanoparticles attenuate lung cancer proliferation and migration

KR Paudel, MSB Mohamad, G De Rubis… - Journal of Drug Delivery …, 2024 - Elsevier
Conventional treatment methods to treat lung cancer include radiation therapy,
chemotherapy, and immunotherapy. However, they cause severe adverse effects and …

[HTML][HTML] Cellular senescence in lung cancer: Molecular mechanisms and therapeutic interventions

SK Jha, G De Rubis, SR Devkota, Y Zhang… - Ageing Research …, 2024 - Elsevier
Lung cancer stands as the primary contributor to cancer-related fatalities worldwide,
affecting both genders. Two primary types exist where non-small cell lung cancer (NSCLC) …

Ribavirin attenuates carcinogenesis by downregulating IL-6 and IL-8 in vitro in human lung adenocarcinoma

G De Rubis, KR Paudel, S Yeung, V Agarwal… - … -Research and Practice, 2024 - Elsevier
Lung cancer is one of the leading causes of death worldwide, whereby the major
contributing factors are cigarette smoking and exposure to environmental pollutants. Despite …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

Non-coding RNAs as key regulators of Gasdermin-D mediated pyroptosis in cancer therapy

G Gupta, M Afzal, E Moglad, H Ali, TG Singh… - … -Research and Practice, 2024 - Elsevier
Pyroptosis is an inflammatory programed cell death process that plays a crucial role in
cancer therapeutic, while Gasdermin-D is a critical effector protein for pyroptosis execution …

Nanoemulsion therapy: a paradigm shift in lung cancer management

R Pahwa, G Sharma, J Chhabra, T Haider… - Journal of Drug Delivery …, 2024 - Elsevier
Lung carcinoma is classified as one of the most severe lethal malignancies and
characterized by unregulated cellular proliferation. Given the vast array of medicinal …

Crosstalk between ROS-inflammatory gene expression axis in the progression of lung disorders

S Ashique, N Mishra, S Mantry, A Garg… - Naunyn-Schmiedeberg's …, 2024 - Springer
A significant number of deaths and disabilities worldwide are brought on by inflammatory
lung diseases. Many inflammatory lung disorders, including chronic respiratory emphysema …

Antibiotic-loaded nano-sized delivery systems: an insight into gentamicin and vancomycin

S Pisani, S Tufail, M Rosalia, R Dorati… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
The fight against infectious disease has remained an ever-evolving challenge in the
landscape of healthcare. The ability of pathogens to develop resistance against …