The field of oncology has been changed by the application of hydrogels. These 3D
polymeric networks have demonstrated significant promise in the treatment of cancer and …

The biofabrication of complex human tissues to recapitulate organ-specific architecture and
function requires a combination of engineering control and intrinsic self-assembly. Organoid …

Incomplete understanding of metastatic disease mechanisms continues to hinder effective
treatment of cancer. Despite remarkable advancements toward the identification of …

The transcriptional coactivators yes-associated protein (YAP) and transcriptional coactivator
with PDZ-binding motif (TAZ) are master regulators involved in a multitude of cancer types …

Currently, esophageal adenocarcinoma (EAC) research is hindered by a dearth of adequate
models to study this disease. Traditional cell line and genetically engineered mouse models …

The etiology of gastrointestinal (GI) diseases is intricate and multifactorial, encompassing
complex interactions between genetic predisposition and gut microbiota. The cell fate …

In the last decade, organoid research has entered a golden era, signifying a pivotal shift in
the biomedical landscape. The year 2023 marked a milestone with the publication of …

Cancer is a complex disease driven by genetic mutations, epigenetic modifications, and
alterations in the tumor microenvironment. Understanding these intricate molecular …

Oesophageal cancer (OC), the 12 th most common cancer (UK), presents with high clinical
need and poor survival. OC is histologically divided into adenocarcinoma (OAC) and …