Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Hyperbranched polymers: advances from synthesis to applications

Y Zheng, S Li, Z Weng, C Gao - Chemical Society Reviews, 2015 - pubs.rsc.org
Hyperbranched polymers (HPs) are highly branched three-dimensional (3D)
macromolecules. Their globular and dendritic architectures endow them with unique …

Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects

X Zhang, Y Li, YE Chen, J Chen, PX Ma - Nature communications, 2016 - nature.com
MicroRNAs (miRNAs) are being developed to enhance tissue regeneration. Here we show
that a hyperbranched polymer with high miRNA-binding affinity and negligible cytotoxicity …

Dendritic polyglycerols for biomedical applications

M Calderón, MA Quadir, SK Sharma… - Advanced …, 2010 - Wiley Online Library
The application of nanotechnology in medicine and pharmaceuticals is a rapidly advancing
field that is quickly gaining acceptance and recognition as an independent area of research …

Self‐assembly of hyperbranched polymers and its biomedical applications

Y Zhou, W Huang, J Liu, X Zhu, D Yan - Advanced materials, 2010 - Wiley Online Library
Hyperbranched polymers (HBPs) are highly branched macromolecules with a three‐
dimensional dendritic architecture. Due to their unique topological structure and interesting …

Bioapplications of hyperbranched polymers

D Wang, T Zhao, X Zhu, D Yan, W Wang - Chemical Society Reviews, 2015 - pubs.rsc.org
Hyperbranched polymers (HBPs), an important subclass of dendritic macromolecules, are
highly branched, three-dimensional globular nanopolymeric architectures. Attractive …

Nanoparticles in the biological context: surface morphology and protein corona formation

W Richtering, I Alberg, R Zentel - Small, 2020 - Wiley Online Library
A recent paper demonstrated that the formation of a protein corona is not a general property
of all types of nanosized objects. In fact, it varies between a massive aggregation of plasma …

Supramolecular architectures of dendritic amphiphiles in water

BNS Thota, LH Urner, R Haag - Chemical reviews, 2016 - ACS Publications
Dendritic molecules are an exciting research topic because of their highly branched
architecture, multiple functional groups on the periphery, and very pertinent features for …

Drug delivery by soft matter: matrix and vesicular carriers

E Soussan, S Cassel, M Blanzat… - Angewandte Chemie …, 2009 - Wiley Online Library
The increasing need for drug delivery systems that improve specificity and activity and at the
same time reduce toxicity to ensure maximum treatment safety has led to the development of …

The potential of self-assembled, pH-responsive nanoparticles of mPEGylated peptide dendron–doxorubicin conjugates for cancer therapy

W She, K Luo, C Zhang, G Wang, Y Geng, L Li, B He… - Biomaterials, 2013 - Elsevier
Nanoparticles, such as dendritic polymers, are currently investigated as excellent
candidates for drug delivery vehicles. In this study, we report the preparation and …