Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin
resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis …

Metabolic syndrome (MetS) represents a cluster of metabolic abnormalities that include
hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia, and is …

Barberry (Berberis vulgaris L.) has different medicinal applications in folk medicine of Iran.
Berberine, an alkaloid constituent of this plant, is present in the roots, rhizomes, stem, and …

The increased incidence of metabolic diseases (eg, diabetes and obesity) has seriously
affected human health and life safety worldwide. It is of great significance to find effective …

Significance: Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol
build-up, has been growing in the global world in concert with the raised prevalence of …

The field of Traditional Chinese Medicine (TCM) represents a vast and largely untapped
resource for modern medicine. Exemplified by the success of the antimalarial artemisinin …

Oxidative stress and inflammation are proved to be critical for the pathogenesis of diabetes
mellitus. Berberine (BBR) is a natural compound isolated from plants such as Coptis …

Berberine (BBR) is an isoquinoline plant alkaloid endowed with several pharmacological
activities, including anti-microbial, glucose-and cholesterol-lowering, anti-tumoral and …

Chemical compounds derived from plants have been used since the origin of human beings
to counteract a number of diseases. Among them, the natural isoquinoline alkaloid …

A substantial knowledge on the pathogenesis of diabetes mellitus (DM) by oxidative stress
and inflammation is available. Berberine is a biologically active botanical that can combat …