Multiomics to elucidate inflammatory bowel disease risk factors and pathways

M Agrawal, KH Allin, F Petralia, JF Colombel… - Nature reviews …, 2022 - nature.com
Inflammatory bowel disease (IBD) is an immune-mediated disease of the intestinal tract, with
complex pathophysiology involving genetic, environmental, microbiome, immunological and …

Genetic and epigenetic etiology of inflammatory bowel disease: An update

S Jarmakiewicz-Czaja, M Zielińska, A Sokal, R Filip - Genes, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and
remission of the disease. The etiology of IBD is not fully understood. Many studies point to …

The preventive effect of Glycyrrhiza polysaccharide on lipopolysaccharide-induced acute colitis in mice by modulating gut microbial communities

X Wei, N Li, X Wu, G Cao, H Qiao, J Wang… - International Journal of …, 2023 - Elsevier
Acute colitis is characterised by an unpredictable onset and causes intestinal flora
imbalance together with microbial migration, which leads to complex parenteral diseases …

Chlorogenic acid combined with epigallocatechin-3-gallate mitigates D-galactose-induced gut aging in mice

R Wei, Z Su, GG Mackenzie - Food & Function, 2023 - pubs.rsc.org
Chlorogenic acid (CGA) and epigallocatechin-3-gallate (EGCG) are major polyphenolic
constituents of coffee and green tea with beneficial health properties. In this study, we …

Epigallocatechin gallate (EGCG) promotes the immune function of ileum in high fat diet fed mice by regulating gut microbiome profiling and immunoglobulin …

X Liu, K Zhao, N Jing, Q Kong, X Yang - Frontiers in Nutrition, 2021 - frontiersin.org
This study aimed to investigate the regulatory effect of epigallocatechin gallate (EGCG) on
the composition of the gut microbiome, the transcriptomic profiling of ileum, and their …

Prediction and prevention of inflammatory bowel disease

EW Lopes, W Turpin, K Croitoru, JF Colombel… - Clinical …, 2024 - Elsevier
11 Acknowledgement: We would like to thank the Helmsley Charitable Trust for their
generous 12 support of the PROMISE consortium (PRediction and PRevention through …

[HTML][HTML] The Contribution of Genetic and Epigenetic Factors: An Emerging Concept in the Assessment and Prognosis of Inflammatory Bowel Diseases

H Minea, AM Singeap, M Minea, S Juncu… - International Journal of …, 2024 - mdpi.com
Inflammatory bowel disease (IBD) represents heterogeneous and relapsing intestinal
conditions with a severe impact on the quality of life of individuals and a continuously …

Dietary supplementation with black raspberries altered the gut microbiome composition in a mouse model of colitis-associated colorectal cancer, although with …

DM Rodriguez, KJ Hintze, G Rompato, AJV Wettere… - Nutrients, 2022 - mdpi.com
Black raspberries (BRB) are rich in anthocyanins with purported anti-inflammatory
properties. However, it is not known whether dietary supplementation would ameliorate …

[HTML][HTML] The Role of Host Genetics and Intestinal Microbiota and Metabolome as a New Insight into IBD Pathogenesis

O Zakerska-Banaszak, J Zuraszek-Szymanska… - International Journal of …, 2024 - mdpi.com
Inflammatory bowel disease (IBD) is an incurable, chronic disorder of the gastrointestinal
tract whose incidence increases every year. Scientific research constantly delivers new …

Diagnostic model for predicting hyperuricemia based on alterations of the gut microbiome in individuals with different serum uric acid levels

M Liang, J Liu, W Chen, Y He, M Kahaer, R Li… - Frontiers in …, 2022 - frontiersin.org
Background We aimed to assess the differences in the gut microbiome among participants
with different uric acid levels (hyperuricemia [HUA] patients, low serum uric acid [LSU] …