Cellular responses to environmental stimuli are controlled by a series of signaling cascades
that transduce extracellular signals from ligand-activated cell surface receptors to the …

Since the first discovery of a peptide with RFamide structure at its C-terminus (ie, an
RFamide peptide) from an invertebrate in 1977, numerous studies on RFamide peptides …

Although estrogen is known to activate endothelial nitric oxide synthase (eNOS) in the
vascular endothelium, the molecular mechanism responsible for this effect remains to be …

Whether or not inhibition of NFκB increases the efficacy of cisplatin in in vitro and in vivo
ovarian cancer models was investigated. We compared the basal levels of phosphorylation …

We investigated whether inhibition of nuclear factor-κB (NFκB) increases the efficacy of
paclitaxel in in vitro and in vivo ovarian cancer models. Treatment of paclitaxel-sensitive …

Prolactin-releasing peptide (PrRP) is an RF-amide neuropeptide that binds and activates its
cognate G protein-coupled receptor, prolactin-releasing peptide receptor (PrRPR), also …

RF-amide neuropeptides, with their typical Arg-Phe-NH 2 signature at their carboxyl C-
termini, belong to a lineage of peptides that spans almost the entire life tree. Throughout …

Prolactin-releasing peptide (PrRP) belongs to the large RF-amide neuropeptide family with
a conserved Arg-Phe-amide motif at the C-terminus. PrRP plays a main role in the regulation …

The RFamide peptide family is a group of proteins that share a common C-terminal arginine–
phenylalanine–amide motif. To date, the family comprises five groups in mammals …

Mammalian RF-amide peptides, which all share a conserved carboxyl-terminal Arg–Phe–
NH2 sequence, constitute a family of five groups of neuropeptides that are encoded by five …