Nanodiamonds and their applications in cells

M Chipaux, KJ van der Laan, SR Hemelaar, M Hasani… - Small, 2018 - Wiley Online Library
Diamonds owe their fame to a unique set of outstanding properties. They combine a high
refractive index, hardness, great stability and inertness, and low electrical but high thermal …

Nanodiamonds for in vivo applications

KJ Van Der Laan, M Hasani, T Zheng, R Schirhagl - Small, 2018 - Wiley Online Library
Due to their unique optical properties, diamonds are the most valued gemstones. However,
beyond the sparkle, diamonds have a number of unique properties. Their extreme hardness …

Nanodiamond relaxometry-based detection of free-radical species when produced in chemical reactions in biologically relevant conditions

F Perona Martínez, AC Nusantara, M Chipaux… - ACS …, 2020 - ACS Publications
Diamond magnetometry is a quantum sensing method involving detection of magnetic
resonances with nanoscale resolution. For instance, T1 relaxation measurements, inspired …

Recent advancements in polymer matrix nanocomposites for bone tissue engineering applications

S Sagadevan, R Schirhagl, MZ Rahman… - Journal of Drug Delivery …, 2023 - Elsevier
Several polymer-based nanocomposites have been studied and used for tissue engineering
applications in recent years. These biodegradable nanocomposites have proven …

Diamond‐Based Nanoscale Quantum Relaxometry for Sensing Free Radical Production in Cells

A Sigaeva, H Shirzad, FP Martinez, AC Nusantara… - Small, 2022 - Wiley Online Library
Diamond magnetometry makes use of fluorescent defects in diamonds to convert magnetic
resonance signals into fluorescence. Because optical photons can be detected much more …

Functionalized fluorescent nanodiamonds for simultaneous drug delivery and quantum sensing in HeLa cells

Y Tian, AC Nusantara, T Hamoh, A Mzyk… - … Applied Materials & …, 2022 - ACS Publications
Here, we present multifunctional fluorescent nanodiamonds (FNDs) for simultaneous drug
delivery and free radical detection. For this purpose, we modified FNDs containing nitrogen …

Fluorescent nanodiamonds for detecting free-radical generation in real time during shear stress in human umbilical vein endothelial cells

R Sharmin, T Hamoh, A Sigaeva, A Mzyk… - ACS …, 2021 - ACS Publications
Free-radical generation is suspected to play a key role in cardiovascular diseases. Another
crucial factor is shear stress. Human umbilical vein endothelial cells (HUVECS), which form …

[HTML][HTML] Detecting the metabolism of individual yeast mutant strain cells when aged, stressed or treated with antioxidants with diamond magnetometry

A Morita, AC Nusantara, A Myzk, FPP Martinez… - Nano Today, 2023 - Elsevier
Free radicals play a key role in the ageing process. However, free radicals are small,
reactive and short lived and thus challenging to measure. We utilize a new technique called …

Diamond color centers in diamonds for chemical and biochemical analysis and visualization

A Mzyk, Y Ong, AR Ortiz Moreno, SK Padamati… - Analytical …, 2021 - ACS Publications
Beyond the sparkle, other properties of diamond have gained increasing attention in the
past few decades among chemists and physicists. Color centers impurities formed by one …

Intracellular quantum sensing of free-radical generation induced by acetaminophen (APAP) in the cytosol, in mitochondria and the nucleus of macrophages

R Sharmin, AC Nusantara, L Nie, K Wu… - ACS …, 2022 - ACS Publications
Acetaminophen overdoses cause cell injury in the liver. It is widely accepted that liver toxicity
is initiated by the reactive N-acetyl-para-aminophenol (APAP) metabolite N-acetyl-p …