[HTML][HTML] TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease
Transforming growth factor-beta (TGF-β) and bone morphogenic protein (BMP) signaling
has fundamental roles in both embryonic skeletal development and postnatal bone …
has fundamental roles in both embryonic skeletal development and postnatal bone …
Cartilage tissue engineering: molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction
M Demoor, D Ollitrault, T Gomez-Leduc… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Background Articular cartilage defects are a veritable therapeutic problem because
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …
therapeutic options are very scarce. Due to the poor self-regeneration capacity of cartilage …
Mesenchymal precursor cells in the blood of normal individuals
NJ Zvaifler, L Marinova-Mutafchieva, G Adams… - Arthritis Research & …, 2000 - Springer
Statement of findings Mesenchymal precursor cells found in the blood (BMPCs) of normal
persons adhere to plastic and glass and proliferate logarithmically in DMEM-20% fetal calf …
persons adhere to plastic and glass and proliferate logarithmically in DMEM-20% fetal calf …
Structural basis of BMP signalling inhibition by the cystine knot protein Noggin
The interplay between bone morphogenetic proteins (BMPs) and their antagonists governs
developmental and cellular processes as diverse as establishment of the embryonic dorsal …
developmental and cellular processes as diverse as establishment of the embryonic dorsal …
Current views on calcium phosphate osteogenicity and the translation into effective bone regeneration strategies
Calcium phosphate (CaP) has traditionally been used for the repair of bone defects because
of its strong resemblance to the inorganic phase of bone matrix. Nowadays, a variety of …
of its strong resemblance to the inorganic phase of bone matrix. Nowadays, a variety of …
BMP2 signaling in bone development and repair
V Rosen - Cytokine & growth factor reviews, 2009 - Elsevier
BMPs are best known for their actions as bone formation signals. Recent studies using
transgenic mice in which individual osteogenic BMPs have been removed from the limb …
transgenic mice in which individual osteogenic BMPs have been removed from the limb …
Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo
BS Yoon, DA Ovchinnikov, I Yoshii… - Proceedings of the …, 2005 - National Acad Sciences
Previous studies have demonstrated the ability of bone morphogenetic proteins (BMPs) to
promote chondrogenic differentiation in vitro. However, the in vivo role of BMP signaling …
promote chondrogenic differentiation in vitro. However, the in vivo role of BMP signaling …
BMP signaling in skeletal development
Development of the vertebrate skeleton, a complex biological event that includes diverse
processes such as formation of mesenchymal condensations at the sites of future skeletal …
processes such as formation of mesenchymal condensations at the sites of future skeletal …
Generation of articular chondrocytes from human pluripotent stem cells
AM Craft, JS Rockel, Y Nartiss, RA Kandel… - Nature …, 2015 - nature.com
The replacement of articular cartilage through transplantation of chondrogenic cells or
preformed cartilage tissue represents a potential new avenue for the treatment of …
preformed cartilage tissue represents a potential new avenue for the treatment of …