Copy number variation in the genomes of domestic animals

A Clop, O Vidal, M Amills - Animal genetics, 2012 - Wiley Online Library
Copy number variation (CNV) might be one of the main contributors to phenotypic diversity
and evolutionary adaptation in animals and plants, employing a wide variety of mechanisms …

A comprehensive survey of copy number variation in 18 diverse pig populations and identification of candidate copy number variable genes associated with complex …

C Chen, R Qiao, R Wei, Y Guo, H Ai, J Ma, J Ren… - BMC genomics, 2012 - Springer
Background Copy number variation (CNV) is a major source of structural variants and has
been commonly identified in mammalian genome. It is associated with gene expression and …

Copy number variation of individual cattle genomes using next-generation sequencing

DM Bickhart, Y Hou, SG Schroeder, C Alkan… - Genome …, 2012 - genome.cshlp.org
Copy number variations (CNVs) affect a wide range of phenotypic traits; however, CNVs in
or near segmental duplication regions are often intractable. Using a read depth approach …

Genomic characteristics of cattle copy number variations

Y Hou, GE Liu, DM Bickhart, MF Cardone, K Wang… - BMC genomics, 2011 - Springer
Background Copy number variation (CNV) represents another important source of genetic
variation complementary to single nucleotide polymorphism (SNP). High-density SNP array …

Liver transcriptome profile in pigs with extreme phenotypes of intramuscular fatty acid composition

Y Ramayo-Caldas, N Mach, A Esteve-Codina… - BMC genomics, 2012 - Springer
Background New advances in high-throughput technologies have allowed for the massive
analysis of genomic data, providing new opportunities for the characterization of the …

Evolutionary dynamics of copy number variation in pig genomes in the context of adaptation and domestication

Y Paudel, O Madsen, HJ Megens, LAF Frantz, M Bosse… - BMC genomics, 2013 - Springer
Background Copy number variable regions (CNVRs) can result in drastic phenotypic
differences and may therefore be subject to selection during domestication. Studying copy …

Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins

L Jiang, J Jiang, J Yang, X Liu, J Wang, H Wang… - BMC genomics, 2013 - Springer
Abstract Background Copy number variations (CNVs) are widespread in the human or
animal genome and are a significant source of genetic variation, which has been …

Analysis of copy number variations in the sheep genome using 50K SNP BeadChip array

J Liu, L Zhang, L Xu, H Ren, J Lu, X Zhang, S Zhang… - BMC genomics, 2013 - Springer
Background In recent years, genome-wide association studies have successfully uncovered
single-nucleotide polymorphisms (SNPs) associated with complex traits such as diseases …

CNV discovery for milk composition traits in dairy cattle using whole genome resequencing

Y Gao, J Jiang, S Yang, Y Hou, GE Liu, S Zhang… - BMC genomics, 2017 - Springer
Abstract Background Copy number variations (CNVs) are important and widely distributed in
the genome. CNV detection opens a new avenue for exploring genes associated with …

Diversity and population-genetic properties of copy number variations and multicopy genes in cattle

DM Bickhart, L Xu, JL Hutchison, JB Cole… - DNA …, 2016 - academic.oup.com
The diversity and population genetics of copy number variation (CNV) in domesticated
animals are not well understood. In this study, we analysed 75 genomes of major taurine …