Antibody evasion associated with the RBD significant mutations in several emerging SARS-CoV-2 variants and its subvariants

M Bhattacharya, S Chatterjee, SS Lee, K Dhama… - Drug Resistance …, 2023 - Elsevier
Since the origin of the wild strain of SARS-CoV-2, several variants have emerged, which
were designated as VOC, VOI, and VUM from time to time. The Omicron variant is noted as …

Facing the challenges in the COVID-19 pandemic era: from standard treatments to the umbilical cord-derived mesenchymal stromal cells as a new therapeutic strategy

E Russo, S Corrao, F Di Gaudio, G Alberti, M Caprnda… - Cells, 2023 - mdpi.com
Coronavirus disease 2019 (COVID-19), the pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), which counts more than 650 million cases and …

Genome‐based comparison between the recombinant SARS‐CoV‐2 XBB and its parental lineages

F Scarpa, D Sanna, I Azzena, M Casu… - Journal of Medical …, 2023 - Wiley Online Library
Recombination is the main contributor to RNA virus evolution, and SARS‐CoV‐2 during the
pandemic produced several recombinants. The most recent SARS‐CoV‐2 recombinant is …

Evolving real-world effectiveness of monoclonal antibodies for treatment of COVID-19: a cohort study

KE Kip, EK McCreary, K Collins, TE Minnier… - Annals of Internal …, 2023 - acpjournals.org
Background: Treatment guidelines and US Food and Drug Administration emergency use
authorizations (EUAs) of monoclonal antibodies (mAbs) for treatment of high-risk outpatients …

Cationic crosslinked carbon dots-adjuvanted intranasal vaccine induces protective immunity against Omicron-included SARS-CoV-2 variants

H Lei, A Alu, J Yang, X He, C He, W Ren… - Nature …, 2023 - nature.com
Mucosal immunity plays a significant role in the first-line defense against viruses transmitted
and infected through the respiratory system, such as SARS-CoV-2. However, the lack of …

Multiple mutations of SARS-CoV-2 Omicron BA. 2 variant orchestrate its virological characteristics

I Kimura, D Yamasoba, H Nasser, H Ito… - Journal of …, 2023 - Am Soc Microbiol
Previous studies on the Omicron BA. 2 variant suggested that the virological characteristics
of BA. 2 are determined by the mutations in at least two different regions of the viral genome …

Genetic and structural analyses reveal the low potential of the SARS‐CoV‐2 EG. 5 variant

F Scarpa, S Pascarella, A Ciccozzi… - Journal of Medical …, 2023 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 EG. 5 lineage is the latest variant
under monitoring, and it is generating significant concern due to its recent upward trend in …

COVID-19: understanding the new variants of concern

KY Loo, V Letchumanan - Progress In Microbes & …, 2022 - journals.hh-publisher.com
The novel coronavirus, SARS-CoV-2, part of the Coronaviridae family, was discovered in
December 2019 in China. World Health Organization named it COVID-19 and by March …

Discovery of novel papain-like protease inhibitors for potential treatment of COVID-19

F Hersi, A Sebastian, H Tarazi, V Srinivasulu… - European Journal of …, 2023 - Elsevier
The recent emergence of different SARS-CoV-2 variants creates an urgent need to develop
more effective therapeutic agents to prevent COVID-19 outbreaks. Among SARS-CoV-2 …

SARS-CoV-2 Recombinants: Genomic Comparison between XBF and Its Parental Lineages

F Scarpa, C Locci, I Azzena, M Casu, PL Fiori… - Microorganisms, 2023 - mdpi.com
Recombination events are very common and represent one of the primary drivers of RNA
virus evolution. The XBF SARS-CoV-2 lineage is one of the most recently generated …